Ep 333: Homocysteine: The Hidden Marker Linked to Mood, Memory & Hormones

In this episode I’m diving into one small but powerful blood marker you’ve probably never been offered at the GP: homocysteine. We look at: What homocysteine actually is and why it matters for your mood, memory and hormones How B6, B12 and folate can help lower homocysteine The Oxford VITACOG trial showing B-vitamins can slow brain shrinkage in people with mild cognitive impairment Follow-up research showing B-vitamins work best when omega-3 levels are good – why your brain needs both B-vitamins and omega-3s together Practical ways to support healthy homocysteine levels through food, supplements and testing Studies mentioned in this episode: Smith AD et al. Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment (PLoS ONE, 2010): PubMed Oulhaj A et al. Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment (J Alzheimers Dis, 2016): PubMed Resources & links: Book a ROOT deep-dive session with me:

You can listen to Ep 333: Homocysteine: The Hidden Marker Linked to Mood, Memory & Hormones online on Radio and Podcast. Open the player on this page to stream the available audio.

Ep 333: Homocysteine: The Hidden Marker Linked to Mood, Memory & Hormones is an episode from The Gut Goddess Show with Kezia Hall by Kezia Hall.

This episode is 32:40 long.

This episode was published on Dec 3, 2025.

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