Why Endometriosis Keeps Coming Back (And How to Break the Cycle)

Endometriosis affects 1 in 10 women yet it often takes years to diagnose, and many are told their pain is “normal” or simply treated with birth control or surgery. But endometriosis isn’t just a hormone issue—it’s a whole-body condition driven by inflammation, immune dysfunction, gut health, and environmental exposures. In this episode, we break down what’s really causing it and what you can do to address it at the root. I’m joined by my longtime colleague and friend, Dr. Elizabeth Boham, Medical Director and Functional Medicine Physician at The UltraWellness Center. Here’s what we break down: • Why endometriosis is not just a gynecologic condition and the root causes most doctors miss • The hidden role of gut health, inflammation, and the microbiome in driving symptoms • How estrogen imbalance and environmental toxins (xenoestrogens) fuel the condition • A functional medicine approach to reducing pain and preventing recurrence beyond medication or surgery If you’re struggling with endometriosis or unresolved symptoms and want a more personalized, root-cause approach, you can learn more about becoming a patient at The UltraWellness Center here: Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year. Have a question you’d love answered on Office Hours? Submit it here (0:00) Introduction, statistics, and overview of endometriosis and functional medicine (2:27) Introduction of Dr. Elizabeth Boham and explanation of endometriosis (6:10) The immune system, gut health, and their roles in endometriosis (10:29) The gut microbiome, estrogen metabolism, and the 5R approach (16:55) Xenoestrogens and detoxification strategies (22:53) Nutritional supplements and additional detox support (25:41) Surgery and lifestyle interventions for endometriosis management (30:20) Blood sugar, insulin resistance, and hormonal balance (32:11) Prevention and recurrence of endometriosis (33:40) Summary, key takeaways, and closing remarks (38:11) Sponsor: Gratitude to sponsors

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Why Endometriosis Keeps Coming Back (And How to Break the Cycle) is an episode from The Doctor's Farmacy with Mark Hyman, M.D. by Dr. Mark Hyman.

This episode is 40:26 long.

This episode was published on Mar 30, 2026.

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