310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More

We had some HYPOTHESES for this amazing episode! The main topics all revolved around fatigue resistance (often called “durability” in the literature), which we think is the most exciting area of training theory and physiology. It started with Rachel Entrekin’s legendary overall win at the Cocodona 250, an event that explores some of the strangest and coolest parts of endurance. Our big theory: what we’re seeing in these wild ultras is directly connected to what we see in short distances. A new study looked at fatigue resistance variations between men and women, with some shocking results. We expand the scope to talk about the literature generally before going to some ideas for how it all might relate to the central nervous system. ...And how it relates to fueling. You could probably guess that we were going to talk about carbs. Plus, we answer questions about the culture of fueling for young athletes and feeling good after long runs! This one starts with a description of Megan’s health journey. The hottest vacation is apparently a 3-day stay in Boulder Community Hospital. Things are scary, but we’re holding onto hope for the future. We love you all! HUZZAH! -David and Megan Click "Get 40% Off" button for 40% off at The Feed here: thefeed.com/swap Buy Janji's amazing gear: (code "SWAP") The Wahoo KICKR Run is the best treadmill on the market: (code “SWAP”) For training plans, weekly bonus podcasts, heart rate zones, articles, and videos: patreon.com/swap

You can listen to 310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More online on Radio and Podcast. Open the player on this page to stream the available audio.

310. The Fatigue Resistance Episode! Rachel Entrekin Makes History at Cocodona, Women v. Men Durability, Fueling and the Central Nervous System, Brain Changes, and More is an episode from Some Work, All Play by David Roche and Megan Roche.

This episode is 01:34:02 long.

This episode was published on May 12, 2026.

Yes. Use the heart button on the episode page to add it to your favorite episodes list.

Yes. This page shows related episodes from Some Work, All Play when more episodes are available from the podcast feed.