Episode 481: Is Your Magnesium Working For You? Relax and Regulate Reformulation

Have you tried magnesium but felt like it didn’t help—or even made things worse? Are you confused by all the different forms and dosages? In this episode, Ali and Becki break down how magnesium actually works in the body, why so many people think they “don’t tolerate” magnesium, and why form, dose, and context matter far more than most realize. We also share the full story behind the reformulation of Relax & Regulate, our superstar magnesium product. You’ll learn why we chose magnesium bisglycinate paired with myo-inositol, how this combination supports nervous system regulation, sleep, anxiety, blood sugar, and hormone balance, and why it’s especially impactful for PCOS, perimenopause, and stress-driven symptoms. Also in this episode: Why is magnesium so important? Signs of magnesium deficiency Testing magnesium status Cell Science Systems Micronutrient Panel Episode 440 What does HTMA say about your health with guest Kaely McDevitt Anxiety and Magnesium Deficiency Naturally Nourished Episode 470 SSRIs on the Rise The magnesium GABA connection GabaCalm How inositol supports serotonin Why the combination of magnesium and inositol for blood sugar balance Why magnesium deficiency is more pronounced in perimenopause Forms of magnesium and absorption Considerations of magnesium threonate Why glycine matters and antiaging effects Naturally Nourished Episode 331 Homocysteine and Methylation Dosage considerations 1 scoop for maintenance 2+ scoops for PCOS, constipation, high cortisol, pregnancy Kids can start with ⅛-¼ scoop as early as age 2-3 Teens ½-1 scoop to start for acne, anxiety, hormonal concerns This episode is sponsored by Naturally Nourished Relax and Regulate Relax & Regulate has always been a superstar for sleep, stress, and hormone support, and we’ve taken a good thing and made it even better! We’ve seen incredible results with 1000’s of clients using Relax and Regulate literally every day for 10+ years now. We have increased magnesium bisglycinate from 200 mg to 250 mg to match clinical sleep research dosing, kept myo-inositol at the full 4-gram therapeutic dose, and improved the supporting ingredients so the entire formula is better absorbed, better tolerated, and more aligned with what we’re seeing clinically every day. Use code RELAX15 to save 15% on our reformulated Relax and Regulate!

You can listen to Episode 481: Is Your Magnesium Working For You? Relax and Regulate Reformulation online on Radio and Podcast. Open the player on this page to stream the available audio.

Episode 481: Is Your Magnesium Working For You? Relax and Regulate Reformulation is an episode from Naturally Nourished by Ali Miller RD.

This episode is 57:49 long.

This episode was published on Feb 9, 2026.

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