Enhancing Muscle Quality: A Deep Dive into Mitochondrial Science, Part 1

Urolithin A (MitoPure)--Mitophagy, Muscle Recovery, Immunity, and Skin Health: Dr. Brad Currier, clinical trial manager at Timeline , a Swiss biotech company, details urolithin A (MitoPure), a postbiotic derived from pomegranate precursors that most people cannot produce due to microbiome differences. Currier explains MitoPure’s mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting improved recovery, plus trials in middle-aged and older adults showing improvements in strength, six-minute walk test, and VO2 max at 500 mg–1 g doses. They also cover a Nature Aging immune study reporting rejuvenation of stem-like CD8 T cells with improved mitochondrial fatty acid oxidation, ongoing research directions, supplement quality/testing for athletes, and topical urolithin A skincare trials and partnerships, including L’Oréal Lancôme.

You can listen to Enhancing Muscle Quality: A Deep Dive into Mitochondrial Science, Part 1 online on Radio and Podcast. Open the player on this page to stream the available audio.

Enhancing Muscle Quality: A Deep Dive into Mitochondrial Science, Part 1 is an episode from Intelligent Medicine by Dr. Ronald Hoffman.

This episode is 31:06 long.

This episode was published on May 5, 2026.

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