343: Nucleotides to the Defense

TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Martin Become a patron of TWiM. Links for this episode: Decoy cyclic nucleotides in phage defense (Nature) CRISPR defense with nucleotides (Nature) A decoy defence molecule to set a trap for viruses (Nature) Cyclic oligonucleotide-based antiphage signaling system immunity (Curr Opin Immunol) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

You can listen to 343: Nucleotides to the Defense online on Radio and Podcast. Open the player on this page to stream the available audio.

343: Nucleotides to the Defense is an episode from This Week in Microbiology by American Society for Microbiology.

This episode is 43:57 long.

This episode was published on Oct 25, 2025.

Yes. Use the heart button on the episode page to add it to your favorite episodes list.

Yes. This page shows related episodes from This Week in Microbiology when more episodes are available from the podcast feed.