What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447

My favorite creatine (discount code DAVETUBE): Creatine isn’t just for bodybuilders. It’s one of the most overlooked, science-backed nootropics for brain optimization, neuroplasticity, mitochondrial energy, and total human performance. This episode reveals why creatine is a non-negotiable supplement for anyone serious about biohacking, longevity, and cognitive upgrades. Host Dave Asprey breaks down the myths and truths about creatine, uncovering how it enhances memory, supports your mitochondria, regulates mood, strengthens bones and heart function, and even aids fetal brain development during pregnancy. Drawing from decades of functional medicine, real-world biohacks, and new research featured in the Wall Street Journal, Dave explains how creatine works not only as a muscle booster but as a universal cellular fuel that supports brain benefits, memory improvement, and sleep optimization. Timestamps: 0:00 – Introduction 1:14 – Why Creatine Matters 5:01 – History of Creatine 6:09 – Debunking the Myths 8:55 – 5 Ways Creatine Fuels Your Mind & Body 16:25 – How to Maximize Absorption 18:13 – Dosing: How Much & When to Take It 19:07 – Forms of Creatine Explained 19:50 – Special Use Cases 21:28 – Biohacking Real-World Applications 23:21 – What to Stack with Creatine 24:50 – Choosing the Right Creatine 28:40 – Recap & Key Takeaways Thank you to our sponsors! Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body. AquaTru | Go to and save $100 on all AquaTru water purifiers. Connect with Dave Asprey! Website: TikTok: Instagram: Facebook: X: YouTube: The Human Upgrade Podcast: Danger Coffee: Dave Asprey’s BEYOND Conference: Dave Asprey’s New Book - Heavily Meditated: Dave's favorite supplements: Upgrade Labs: 40 Years of Zen: See Privacy Policy at and California Privacy Notice at .

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What Doctor's DON'T Tell You About Megadosing Creatine (Over 40) : 1447 is an episode from The Human Upgrade with Dave Asprey—formerly Bulletproof Radio by Dave Asprey.

This episode is 00:30:40 long.

This episode was published on Apr 12, 2026.

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