Caffeine, Tolerance, and Getting Your Pre-Workout to Work Again with Dr. Eric Trexler

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Dr. Eric Trexler's Links: RP article: Caffeine, The Double-Edged Sword Stronger by Science: The Lifter's Guide to Caffeine Instagram: @trexlerfitness ResearchGate: Eric Trexler publications Twitter/X: @EricTrexler Timestamps: 00:00 Eric and Nick's BEEF 🥩 06:53 Caffeine's prevalence in fitness 09:10 Eric's caffeine research background 11:04 Daily caffeine intake (1g/day of caffiene safe?) 17:30 Effective dosing by bodyweight and when high doses backfire 22:30 Tolerance and habituation: why your caffeine stops working 30:15 Caffeine withdrawal: symptoms, timeline, and how bad it actually gets 41:30 Caffeine sensitivity and genetics 44:00 Practical upper limits and sleep tradeoffs 48:00 Strategic caffeine use, deloads, and re-sensitizing 50:15 Different delivery forms: drinks, food, pills, and gum 53:45 Does caffeine Dehydrate you? Wrap-up and where to read more

You can listen to Caffeine, Tolerance, and Getting Your Pre-Workout to Work Again with Dr. Eric Trexler online on Radio and Podcast. Open the player on this page to stream the available audio.

Caffeine, Tolerance, and Getting Your Pre-Workout to Work Again with Dr. Eric Trexler is an episode from RP Strength Podcast by Dr. Mike Israetel, Nick Shaw.

This episode is 54:26 long.

This episode was published on Mar 30, 2026.

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