Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular system. What’s particularly compelling in this new preclinical research is that restoring mitochondrial function may do more than just improve ejection fraction. It may also have ripple effects on other hallmarks of aging—like chronic inflammation, cellular stress signaling, and impaired autophagy. I’m thrilled Timeline is continuing to invest in both preclinical and clinical research on this front—and yes, I’m totally nerding out over what they’re up to. ~DrK Check out the show notes at for the full list of links and resources. GUEST DETAILS Davide D'Amico, PhD: Director of Discovery and Translational Research at Timeline. With over 15 years of experience in mitochondrial and aging biology, he contributed to developing Urolithin A as a science-backed, clinically validated nutritional product to enhance mitochondrial and muscle health. THANKS TO OUR SPONSOR Timeline: Email: care@timeline.com EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Mitopure is making impressive strides for cellular health and longevity. Get 10% off your first order at with code Kara10. CONNECT with DrKF Want more? Join our newsletter here: Or take our pop quiz and test your BioAge! YouTube: Instagram: Facebook: DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: Younger You book: Better Broths and Healing Tonics book:

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Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix is an episode from New Frontiers in Functional Medicine by Dr. Kara Fitzgerald - Functional Med & Longevity.

This episode is 00:47:27 long.

This episode was published on Jul 8, 2025.

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