Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making

Neuropsychopharmacology Podcast by Marina Ostankovitch

Jan 4, 20249:33Science & Medicine

Serotonin is a critical chemical when it comes to a number of psychiatric conditions, such as OCD, where it seems to play a particular role in cognitive flexibility. That is, serotonin levels are related to the fact that...

Related Episodes

Continue listening to more episodes from Neuropsychopharmacology Podcast.

Shared genetic architecture and neurobiological pathways of problematic alcohol use and anxiety disorders

Aug 31, 2026 - 7:51

Problematic alcohol use frequently occurs in conjunction with anxiety disorders. Between 20 to 40 percent...

Examining fronto-limbic brain and sleep mechanisms of antidepressant effects in cognitive-behavioral therapy for insomnia

Jul 2, 2026 - 9:58

Insomnia and depression are two serious and debilitating conditions. Insomnia on its own is linked to an...

Incentive salience, not psychomotor sensitization or tolerance, drives escalation of cocaine self-administration in heterogeneous stock rats

May 15, 2026 - 9:43

There are a number of theories that have been studied to try to explain addiction and drug use escalation...

Oxytocin neurons in the anterior and posterior paraventricular nucleus have distinct behavioral functions and electrophysiological profiles

Feb 23, 2026 - 9:44

Oxytocin has become known for having anti-anxiety and affiliative behavioral effects. That’s why clinicia...

Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records

Jun 4, 2025 - 9:41

Attention deficit hyperactivity disorder, or ADHD, is a common condition that, for a lot of people, is di...