The Treatment Toolkit for Liver Cancer and Metastatic Disease, from Surgery to Shockwaves and Beyond

Discover how liver cancer treatment is evolving in this episode of CancerCast. Dr. Manish Shah and Dr. Juan Rocca discuss the liver’s complicated and critical role in cancer care, from its position as a hotspot for metastasis to the role of the liver in impacting how well certain immunotherapy, chemotherapy and other cancer therapies will work. They explore the newest and most cutting-edge treatment options as part of a growing toolkit to personalize treatment for each patient, including open and robotic liver surgery, ablation, and no-cut technologies like histotripsy, using ultrasound shockwaves to liquefy liver tumors while sparing healthy tissue. The conversation also highlights the role and rise of liver transplantation for select cancers, such as colorectal cancer that has spread (metastasized) to the liver, in addition to tumors that start in the liver. There have been many recent treatment advances for both primary liver cancer and metastatic disease, and Drs. Rocca and Shah discuss how combining these new innovations with a team-based, multidisciplinary approach offers patients more options than ever before. Guest: Juan Rocca, MD, Surgical Director of the Weill Cornell Liver Cancer Program and an attending surgeon in the Division of Liver Transplantation and Hepatobiliary Surgery at NewYork-Presbyterian/Weill Cornell Medicine. Host: Manish Shah, MD, Chief of Solid Tumor Service and Director of Gastrointestinal Oncology at Weill Cornell Medicine and NewYork-Presbyterian Hospital.

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The Treatment Toolkit for Liver Cancer and Metastatic Disease, from Surgery to Shockwaves and Beyond is an episode from CancerCast by Weill Cornell Medicine.

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This episode was published on Jan 14, 2026.

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