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CancerCast

Weill Cornell Medicine

New scientific developments are transforming the future of cancer treatment and care. Hosted by world-renowned hematologist and medical oncologist Dr. John Leonard, CancerCast is your window...

Episodes

20 of 79 episodes

GLP-1s and Cancer: Popular Weight Loss Drugs Go Beyond The Scale

GLP-1 (short for glucagon-like peptide-1) medications such as semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) have...

00:35:39Sep 23, 2026

A Breakthrough in Pancreatic Cancer Treatment – KRAS Targeting and Daraxonrasib

Pancreatic cancer treatment has entered an exciting new chapter. On August 26, 2026, the U.S. Food and Drug Administration (FDA) approved th...

00:32:13Aug 28, 2026

ASCO 2026 Highlights

The American Society of Clinical Oncology, or ASCO, Annual Meeting is the world’s largest oncology conference. The meeting brings together c...

00:33:35Jul 31, 2026

Cancer Survivorship – Living With and Beyond Cancer

Thanks to advances in cancer care, more people are living longer after a cancer diagnosis than ever before. People are also being diagnosed...

00:32:53Jun 5, 2026

Understanding Clonal Hematopoiesis: Blood Mutations Linked to Cancer, Heart Disease, Inflammation & More

As we age, our blood cells naturally develop mutations. With new sequencing technology, we can now identify very rare and specific mutations...

May 22, 2026

What are the Latest Advances in Lung Cancer Treatment?

Lung cancer care is changing rapidly and new advances in surgery and medicine are at the forefront. In this episode of CancerCast, Dr. Manis...

Apr 27, 2026

Understanding BiTE Immunotherapy: How Bispecific T-Cell Engagers Target Cancer

Bispecific T-cell engager, or BiTE, therapy is an immunotherapy approach that helps the body’s own immune system target cancer cells by brin...

Mar 20, 2026

The Power of PSMA-Targeted Therapy for Prostate Cancer

Prostate-specific membrane antigen, or PSMA, is a protein expressed on the surface of prostate cancer cells that has become an important tar...

Feb 13, 2026

The Treatment Toolkit for Liver Cancer and Metastatic Disease, from Surgery to Shockwaves and Beyond

Discover how liver cancer treatment is evolving in this episode of CancerCast. Dr. Manish Shah and Dr. Juan Rocca discuss the liver’s compli...

Jan 14, 2026

Key Insights from ASH 2025

In this episode of CancerCast, Dr. Manish Shah is joined by Drs. Gail Roboz and Rick Furman, two internationally renowned Weill Cornell lead...

Dec 3, 2025

Liquid Biopsy: Cancer’s Clues in the Blood

A liquid biopsy is a blood test that looks for cancer cells or genetic material, such as DNA, that are shed into the bloodstream in patients...

Nov 21, 2025

Treatment Advances for Mismatch Repair Deficient Colon Cancer and Lynch Syndrome

Mismatch repair deficiency is a condition caused by DNA errors in the body that lead to a high number of mutations, increasing cancer risk....

Oct 28, 2025

Tumor-Infiltrating Lymphocytes (TIL) & Melanoma: A New Era of Treatment

Tumor-infiltrating lymphocyte, or TIL, therapy is a new form of cellular immunotherapy that targets cancer cells by leveraging the body’s im...

Sep 22, 2025

ASCO 2025 Highlights

Drs. Manish Shah and Sarah Rutherford explore the groundbreaking research presented at the 2025 ASCO Annual Meeting. They discuss key develo...

Aug 4, 2025

Transitions, Reflections and the Future of Cancer Care and Research

A familiar voice in a new role. Drs. John Leonard and Manish Shah reflect on the past seven years of cancer care and research as Dr. Leonard...

Jun 23, 2025

Leonard List 2024

Join Dr. John Leonard for his special annual “Leonard List” episode. He shares his top 10 most interesting lymphoma and blood cancer-related...

Nov 26, 2024

The Ins and Outs of Immunotherapy

Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. In the last 10 years, immunotherapy has joined the l...

Oct 23, 2024

ASCO 2024 Highlights

The American Society of Clinical Oncology, or ASCO, Annual Meeting is the largest global oncology conference and features state-of-the-art r...

Jul 31, 2024

Pathology’s Place in Cancer Care

Pathology has a crucial place in the medical field working behind the scenes to ensure patients and their care teams have the most up-to-dat...

Apr 29, 2024

Bone Breakdown: Bone Health & Cancer

The skeletal system keeps the body upright, but did you know that the bones play a number of pivotal roles in the body? From storing mineral...

Mar 27, 2024