
About Changing The Cancer Conversation
Ahead of World Cancer Day 2026, the groundbreaking podcast You, Me and the Big C is back for a special legacy episode about how it changed t...
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The coolest club you never want to be a part of… A candid look at cancer, with Rachael Bland, Deborah James and Lauren Mahon. They are you…but with dodgier cells!

Ahead of World Cancer Day 2026, the groundbreaking podcast You, Me and the Big C is back for a special legacy episode about how it changed t...

Actor and writer, Rosa Hesmondhalgh hosts this legacy episode discussing cancer and the creative arts, and how to remain creative when livin...

Lauren Mahon hosts this legacy episode discussing the cost of having cancer. She speaks with 77-year-old Helen van Bueren who is living alon...

Steve Bland returns to host this legacy episode discussing cancer and single parents. Steve is joined in the studio by Sophie Blake, who is...

We wanted to share this podcast with you. In the week in which King Charles III shared his cancer diagnosis, Amol Rajan and Nick Robinson as...

Lauren Mahon returns to host this legacy episode discussing cancer and homelessness. Lauren travels to Burnley to meet with Pastor Mick from...

Presenter and broadcaster, Chris Latchem makes an emotional return to the hospital that saved his life to talk to the staff that got him thr...

After meeting during their treatment for breast cancer, Eloise Wynter and Lizzi Amartay host the second episode of this legacy series of pod...

Good friend of the podcast, Tony Livesey hosts the first episode of this brand new series looking into the issues around losing a parent to...

The legacy continues as Lauren Mahon has an exciting announcement about the next series of the 'You, Me and the Big C' podcasts. Episode one...

Lights, camera, reaction! The #YouMeBigC team share their thoughts on the extraordinary documentary about Dame Debs. 'Deborah James: Bowelba...

Lauren Mahon and Steve Bland, alongside producers Mike Holt and Al Entwistle, get together to reflect on the fifth anniversary of You, Me an...

Deborah James' family, medical professionals and members of the cancer community come together to celebrate five years and recognise how the...

Lauren Mahon and Steve Bland get together for a long awaited catch up. They then bring in producers Mike Holt and Al Entwistle for a very ex...

Lauren Mahon, Steve Bland, producers Mike Holt and Al Entwistle recount treasured stories and memories of Deborah James: friend, broadcaster...

BBC Radio 5 Live's Tony Livesey celebrates the life of You, Me & The Big C broadcaster Dame Deborah James.

As Deborah James stops active treatment for her cancer, she speaks with Producer Mike one last time. Join the conversation and the online co...

Lozza and Steve catch up with Deborah about her hospital recordings, how she feels now and what the immediate future looks like. We also say...

After three weeks in hospital Deborah James is finally told she can go home. But nothing ever seems to run smoothly. Little did Debs know th...

Deborah is joined by Lauren as they go through some of recordings she made in hospital. The conversation and recording range from the challe...

On the day our previous podcast came out Deborah James suffered a serious medical emergency. While in hospital she started recording her exp...

After five months away from the pod, the team are back together and Deborah updates Lauren and Steve on the latest developments with her hea...

Steve and Lauren check in with Deborah from her hospital chemo chair. They all talk about life now the Covid restrictions have been lifted a...

Steve Bland is flying solo this week as he asks why men sometimes find it hard to talk and to share their stories. He’s joined by Danny de B...

Deborah James is joined by fellow stage four’ers Emma Campbell and Darren Roberts to talk about hitting rock bottom, what happens physically...

Deborah speaks with Lauren and Steve about the latest changes with her cancer, the complications, resulting adjustments to her treatment and...

For the first time Lauren sits down with her mum, Tina, who is 31 years on from her own cancer diagnosis, to discuss the fear of cancer recu...

Deborah James, Lauren Mahon and Steve Bland are back together again to talk cancer headlines, geek of the week and share your 'laugh or you'...

Lauren is joined by relationship and sex psychotherapist Miranda Christophers to answer your questions on how to regain confidence and intim...

The team get together for an update on Debs' latest developments, discover what organoids are, reflect on reactions to the last two #YouMeBi...

Julia Samuel, a psychotherapist who has spent over 30 years working with bereaved families and TV chef Tim Bilton who has a rare stage 4 mel...

Deborah James hosts a special podcast talking about the challenges of dealing with cancer treatment and diagnosis during the Covid-19 pandem...

Deborah, Steve and Lauren are back for a new series. Debs shares how her treatment is going, including an explanation of the latest cutting-...

It’s been a very testing 12 months for everyone, so Deborah, Lauren and Steve finish 2020 hearing some positive stories, outlooks and reflec...

Lauren and Steve are joined by Kreena Dhiman, Sophie Beresiner and Laura Boyd to discuss their experiences of surrogacy and cancer. Each sha...

Sex, dating and relationships educator Lala and Sinead Collins from GM Cancer, also previously an oncology advanced practitioner, join Debs...

Medical Advisor for Melanoma UK and Clinical Lead for Skin Cancer at the Royal Stoke University Hospital, Wayne Jaffe, joins #YouMeBigC. Kat...

Dr Naureen Starling, a Consultant Medical Oncologist specialising in the treatment of gastrointestinal cancers and Cariad Lloyd, presenter o...

Steph Blackwell, finalist from The Great British Bake Off and her dad, Roger, who has prostate and bowel cancer, join Debs, Lauren and Steve...

Professor Charlie Swanton, Cancer Research UK's Chief Clinician, who is leading ground-breaking studies into lung cancer and Joanna Heard, w...

Internationally acclaimed audio storyteller Sophie Townsend joins Deborah, Lauren and Steve to discuss the story and experiences behind her...

Dr David Crosby, Head of Prevention and Early Detection Research at Cancer Research UK, joins Deborah, Lauren and Steve to talk about what t...

Lauren, Debs and Steve mark the start of Breast Cancer Awareness month with a jam packed episode! Dr Zoe Williams joins the team to talk abo...

Karol Sikora, an oncologist for 50 years and former Director of the World Health Organisation's cancer programme and Katharina Hauck, a Read...

Emma Dutton co-founder of Untangle Grief and the artist behind Grief Kid join Lauren, Debs and Steve to discuss how they are helping people...

Tina Seymour, chief executive of Hope For Tomorrow, joins Debs, Lauren and Steve to talk about how the charity provides mobile cancer care u...

After the death of her son, aged just 23 months, Leanne Fisher and her husband co-founded Fletcher's Fund - a small charity with the aim of...

Executive producer Lucie Kon and director Chris Alcock of Panorama’s 'Britain’s Cancer Crisis' join Deborah, Lauren and Steve to give a fasc...

Kelly Smith, known on social media as Kickass Kell, talks to Deborah, Lauren and Steve about her cancer treatment during the coronavirus pan...

Before lockdown, we'd started to record a new series speaking to gamechangers in the cancer community. Our first recording was with Leanne P...