The accidental rise of Botox

One of the deadliest poisons known to man is now used to treat wrinkles, migraines, and even, maybe, depression. How did that happen? Guests: Jean Carruthers, ophthalmologist and “godmother” of cosmetic Botox. David Simpson, neurologist at Mount Sinai hospital in New York. Axel Wollmer, psychiatrist at the Asklepios clinic in Hamburg, Germany. For more, go to It’s a great place to sign up for our newsletter, view show transcripts, and read more about the topics on our show. Also, email us! unexplainable@vox.com We read every email. Support Unexplainable by making a financial contribution to Vox! bit.ly/givepodcasts Learn more about your ad choices. Visit podcastchoices.com/adchoices Learn more about your ad choices. Visit podcastchoices.com/adchoices

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The accidental rise of Botox is an episode from Unexplainable by Vox.

This episode is 29:02 long.

This episode was published on Mar 18, 2026.

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