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From research on cancer vaccines to why we feel pain, Genentech scientists are tackling some of the biggest challenges in human biology. Want to find out what they’re working on? Pull up a s...
Breakthroughs in the last decade have transformed how we understand and treat multiple sclerosis (MS), but what will it take to stop the dis...
We’re kicking off season seven with an in-depth look at the wild world of ophthalmology, where scientists are pushing the boundaries of what...
Your favorite science podcast is back! To kick off season seven of Two Scientists Walk Into a Bar, hosts Maria Wilson and Danielle Mandikian...
In our season six finale, we dive deeper into how artificial intelligence (AI) is shaping the future of drug discovery and scientific resear...
From our first breath, the air we breathe and our genes shape how our lungs function. It’s a complex interplay we began exploring in our sea...
Cell therapy holds immense potential to transform the way we treat conditions in oncology, ophthalmology, autoimmune disorders, and a wide r...
Digital twins are virtual models of real-world systems that have been gaining momentum as a powerful tool in drug discovery and development....
Each season we discuss new, exciting breakthroughs in cancer research. With evolving technologies enhancing how we understand and target the...
We published our first episode on the threat of antibiotic resistance in 2016, and nearly a decade later, it remains one of the world’s most...
As we kick off season six, we’re diving deeper into one of our most popular topics from last season – our evolving understanding of obesity....
Join Danielle Mandikian and Maria Wilson as they kick off season six of Two Scientists Walk Into A Bar. Hear what they’ve been up to in the...
Machine learning and generative AI are transforming the ways we live and work, but how do these tools fit into the landscape of drug discove...
Small molecules, antibodies, gene therapies – there are so many types of medicines scientists can consider when developing a new treatment f...
Did you know that scientists can grow three-dimensional, miniature versions of human organs in a dish? These tiny in vitro models, known as...
To defeat cancer, we need to understand it better. How does it grow? How do we detect it early? And most importantly, how do we treat it? In...
What drives metabolic conditions like obesity? In this special episode, co-host and cardiovascular disease expert Maria Wilson, gRED Executi...
Antibodies are proteins produced by our immune system that neutralize or help destroy abnormal cells and foreign agents, like bacteria and v...
Many health conditions require medicines that can be delivered to specific parts of the body. For instance, someone with asthma requires med...
Imagine the eyes as cameras, where the cornea acts as the lens and the retina as the film. As with a camera, if something goes wrong in the...
Computational approaches have revolutionized how we interpret data. With the advent of genomic sequencing, scientists can derive significant...
Join Danielle Mandikian and Maria Wilson as they kick off season five of Two Scientists Walk Into a Bar. Hear about their recent lab adventu...
When we consider how a vaccine works, we typically think about vaccines that prevent infectious disease like flu or measles. But another typ...
Because disease outcomes and responses to treatment can vary across populations, clinical research must include patients who are racially, e...
Achieving the first complete sequence of a human genome via the Human Genome Project represents an incredible feat – but it’s just the tip o...
Bacteria – and their constant ability to rapidly evolve and adapt – represent a scientific challenge that’s equal parts fascinating and disc...
Understanding what happens in the brain is notoriously difficult, but scientists have made progress in the past few decades. For Alzheimer’s...
Taking a deep breath can seem like a simple process; however, for millions of people with asthma, inflammation of the airways could make it...
Our understanding of what causes multiple sclerosis (MS) has transformed over the last few decades. While discoveries of the cell types invo...
Two Scientists Walk Into A Bar is back for a fourth season with new hosts, Maria Wilson and Danielle Mandikian! Get to know the new hosts an...
Cells are the basic unit of life, with a remarkable ability to sense their environment, process information and adapt accordingly. With 37.2...
The biological mysteries of age-related diseases have intrigued scientists for decades. In recent years, our expansive knowledge of genetics...
In Season 1, we talked about using biomarkers and big data to match patients with the best treatment for their disease. In this episode, Jan...
Our eyes are our windows to the world, but what happens when those windows start to fade or disappear? To understand how the eye works, scie...
It’s easy to think of cancer as an invader to the body. But in reality, it’s simply the result of a few proofreading errors in DNA replicati...
Last episode, Jane and colleagues unraveled the intricacies of the human microbiome. This week, Jane chats with Mary Keir, Senior Scientist,...
Our bodies are full of bacteria - pounds of them actually. We’re kicking off Season 3 with a closer look at the human microbiome and what ha...
Two Scientists Walk Into a Bar is back for a third season with host Jane Grogan chatting with scientists who are leading the charge to under...
So far this season we’ve talked about the immune system a lot – how immune cells communicate, traffic along connective tissue, and invasive...
Pharmacology is the study of how a medicine works in the body, which is a critical step in understanding what medicines people should be giv...
Neurons, the cells that make up our brain, are some of the most unique cells in our bodies. The complex nature of how they communicate leads...
The lifecycle of a cell mirrors our own lives – cells live and die as we do. It would be easy to think of cell death, or apoptosis, as a neg...
Despite the best efforts of the human immune system, viruses and bacteria are constantly evolving to find new ways to breach our bodies’ nat...
Chemistry is all around us – from the air we breathe, to the food we eat, to the medicine we take when we’re sick. And for the researchers w...
The world of proteins is a minuscule and elegant ballet. Recent advances in imaging techniques have given us unprecedented views into this m...
If your body was a city, then connective tissue would be the infrastructure tying everything together. It’s a hidden universe that helps man...
Jane Grogan and her producer Wellington Bowler are back for a second season of Two Scientists Walk Into a Bar. After a summer hiatus, Jane i...
Designing a clinical trial is fascinatingly complex. There are dozens of variables that could influence the ability of any given trial to be...
Each person’s cancer is unique, so trying to match the right treatment to the right person is one of cancer biology’s biggest remaining chal...
Some types of breast cancer can become “addicted” to estrogen signaling, so treatments that target the estrogen receptor were once thought t...
Bacteria are remarkably fast shape-shifters. As soon as we develop new antibiotics against them, they mutate, leading to drug-resistant stra...