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This Week in Startups

Jason Calacanis

Every day, Jason Calacanis and Molly Wood cover startups, technology, markets, media, crypto, and the all the hottest topics in business and tech. They also interview the world’s greatest fo...

Episodes

20 of 1,498 episodes

Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358

This Week In Startups is made possible by: Paper: https://getpaper.ai/twist G2i: https://G2i.co/twist Northwest Registered Agent: https://ww...

84:06Nov 3, 2026

Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!

This Week In Startups is made possible by: Stripe: https://stripe.com/startups Rippling: https://rippling.ai/twist Northwest Registered Agen...

70:47Oct 30, 2026

Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356

This Week In Startups is made possible by: PayPal: https://paypal.com/business The Conservation Fund: https://www.conservationfund.org/ Host...

72:24Oct 29, 2026

Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355

This Week In Startups is made possible by: Odoo: https://odoo.com/twist G2i: https://g2i.co/twist Rippling: https://rippling.ai/twist Plaud:...

56:48Oct 26, 2026

OpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354

This Week In Startups is made possible by: Plaud - https://plaud.ai/twist Sentry - https://sentry.io/twist Lightfield - https://lightfield.a...

93:11Oct 24, 2026

We asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353

This Week In Startups is made possible by: DigitalOcean - Head to https://do.co/twist to start building on DigitalOcean's AI-Native Cloud to...

101:10Oct 22, 2026

Anthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's Voice

This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.co...

94:19Oct 20, 2026

Flying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)

This Week In Startups is made possible by: Lightfield: https://lightfield.app Every.io: https://every.io/ PayPal: https://paypal.com/busines...

93:19Oct 17, 2026

The Ex-DeepMind Researcher Taking On China’s Open Source AI

This Week In Startups is made possible by: Paper: https://getpaper.ai/twist Superhuman: https://superhuman.com/ Odoo: https://Odoo.com/twist...

60:23Oct 15, 2026

The Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349

This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.co...

80:26Oct 12, 2026

Jason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki Shirato

This Week In Startups is made possible by: Lightfield: https://lightfield.app Rippling: https://Rippling.ai/twist Upwork: https://upwork.com...

84:45Oct 10, 2026

What VCs Really Think About Personal AI Agents | E2347

This Week In Startups is made possible by: Plaud: http://Plaud.ai/twist Odoo: http://Odoo.com/twist Northwest Registered Agent: http://www.n...

78:47Oct 8, 2026

Jason Mentors The Next Generation + Why AI Is Bad at Teaching (Aristotle Interview) | E2346

This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Sentry: http://sentry.io/twi...

70:31Oct 7, 2026

Inside The Startup Building Uncensored AI (Abliteration AI) | EP 2345

This Week In Startups is made possible by: Every.io: http://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/t...

53:15Oct 3, 2026

Justin Kan & Brian Chesky: The Rejections That Built Twitch and Airbnb | E2344

This Week In Startups is made possible by: Plaud: http://Plaud.ai/twist CLA: https://claconnect.com/tech Sentry: http://sentry.io/twist Ligh...

78:04Oct 1, 2026

Jason’s Put a $5K Bounty on His Dream Chrome Extension | E2338

This Week In Startups is made possible by: Every.io: http://every.io/ Northwest Registered Agent: www.northwestregisteredagent.com/twistdoma...

40:46Sep 28, 2026

The 5 Companies Apple Must Buy

This Week In Startups is made possible by: PayPal - https://paypal.com/business Northwest Registered Agent - https://www.northwestregistered...

50:20Sep 28, 2026

A rogue OpenAI agent hacked Australia’s government. Does this matter? | E2342

This Week In Startups is made possible by: https://lightfield.app/ http://getpaper.ai/twist https://conservationfund.org/ http://Plaud.ai/tw...

85:53Sep 25, 2026

VCs Would Bet on Open-Source AI Over OpenAI and Anthropic | E2341

This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: http://Odo...

87:02Sep 23, 2026

Elon's New Hyperloop, Trump's AI Rename, and a Model That Won't Talk | E2340

This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: http://do.co/twist Lightfield: https://lightfiel...

69:39Sep 21, 2026