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This Week in Neuroscience is a podcast about the nervous system.
TWiN explains the finding that activation of intracellular, not plasma membrane, serotonin 2A receptors is responsible for the plasticity-pr...
TWiN explains the role of a ubiquitin ligase component in regulating the sheathing of multiple axons by Schwann cells. Hosts: Vincent Racani...
TWiN explains a study which showed that transplanting gut microbiota from women with fibromyalgia into mice induces pain, as well as phenoty...
TWiN explores the use of speech brain-computer interfaces to restore communication to people with paralysis, and reveals strategies for prot...
TWiN explores how theta phase shifts mediate contextual perception of facial expressions during everyday social interactions. Hosts: Vincent...
TWiN reviews the underlying neurobiological mechanisms of overeating and obesity, the role of the hypothalamus and reward systems in control...
TWiN explains epidemiological data showing that exposure to air pollution was associated with an increased risk of developing Lewy body deme...
TWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects wh...
TWiN discusses research showing that Lactobacillus acidophilus promotes cognitive function recovery after cerebral ischemia, by regulating m...
TWiN explains research which identifies the regions of the brain that register a long-lasting aversion to potentially poisonous food even wi...
TWiN reveals that proteins travel from the blood to the brain where they are taken up by microglia, revealing a new mode of communication be...
TWiN discusses experiments which show that high-fidelity memories that lose their precision with time depends on reorganization of hippocamp...
Tim explains AI co-scientist, a tool released by Google, which it hopes to help scientists generate hypotheses and research proposals, and t...
TWiN explains a study showing that when a mouse is confronted with an unconscious conspecific, it engages in behavior including tongue-dragg...
TWiN discusses a study showing that repetitive injury reactivates HSV-1 in a human brain tissue model and induces phenotypes associated with...
TWiN explains a study showing that while groups of neurons, form the basis for memory, astrocytes are key components of the adaptive reponse...
TWiN explains the identification of a brain circuit and periodic branch-specific neurotransmitter deployment that regulates organismal adapt...
TWiN explores how pregnancy leads to modifications in brain structure and function that may prepare the mother for parenting. Hosts: Vincent...
Joseph Paton and Felipe Rodrigues join TWiN to explain how they used temperature manipulation to alter the speed of neuronal dynamics in the...
Mauro Costa-Mattioli returns to TWiN to discuss the results of a placebo controlled, double blind clinical trial of a probiotic which improv...
TWiN reviews altered somatosensory reactivity, which is frequently observed among individuals with autism spectrum disorders (ASD), and in m...
TWiN reviews experiments which show that SARS-CoV-2 triggers the up-regulation of synaptic components and perturbs local electrical field po...
TWiN welcomes mice to the elite club of 'self-aware' animals, with a study demonstrating a mirror-induced self-directed behavior in mice res...
TWiN describes a study that reveals activation of endogenous retroviruses in oligodenroglia from patients with traumatic brain injury. Hosts...
TWiN explains an amazing study of a man who was paralyzed after a spinal cord injury and regained the ability to walk after implantation of...
TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plas...
TWiN discusses research showing that sciatic nerve activation with electroacupuncture at the sciatic nerve controls systemic inflammation an...
TWiN reviews a mouse model of ADHD to characterize hypersensitivity to pain, and that sensitization is further amplified in a pathological i...
TWiN discusses a study of on the pathways that control opioid analgesic tolerance, a root cause of opioid overdose and misuse, which can dev...
TWiN explains how psychedelic drugs such as LSD, psilocybin, and MDMA, which are being explored for treating a wide range of neuropsychiatri...
Vivianne explains how early in Alzheimer's disease, the brain attempts to counteract the increased excitatory drive caused by amyloid deposi...
Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior used by the brain to st...
Junjie from Jason's lab joins TWiN to discuss the observation that the cell gene PNMA2 encodes non-enveloped virus-like capsids that induce...
TWiN explains the finding that immunity to commensal bacteria promotes sensory neuron regeneration via the cytokine interleukin-17A. Hosts:...
TWiN reviews the field of microgial research, which has advanced in recent decades but is constrained by nomenclature that is necessary but...
TWiN answers listener questions about Alzheimer's disease, glaucoma and the microbiota, Dravet's Syndrome, schizophrenia, brain development,...
Jason and Tim review the use of an implanted chronic deep brain sensing and stimulation device to carry out biomarker-driven closed-loop the...
TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during spinal cord repair...
TWiN describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally beneath the skull. Hosts...
TWiN reviews how, in a mouse stroke model, recovery of movement is associated with the remaining cortex and the striatum coordinating their...
TWiN explains the observation that in mice, the HIV-1 co-receptor CCR5 closes the temporal window for linking different memories. Hosts: Vin...
TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a path...
TWiN explains the finding that in the mouse visual cortex, astrocytes are key elements in the experience-dependent wiring of brain circuits....
TWiN reveals how oligodendrocytes enhance axonal energy metabolism by transcellular delivery of a protein, SIRT2, that deacetylates mitochon...
TWiN discusses the finding that rewiring retinal projections to the auditory thalamus in ferrets leads to visually responsive cells that are...
TWiN reviews evidence in mice that brain neurons encode and retrieve specific immune responses. Become a patron of TWiN! Links for this epis...
TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutroph...
Ioana and Robert join TWiN to discuss their work demonstrating that rodents acquire maternal behavior by social transmission from an experie...
Bruce Carter joins TWiN to discuss the peripheral nervous system: the development of nerves that convey sensory information like touch from...
TWiN explains how anti-DNA antibodies present in lupus patients bind to GluN2A-containing NMDA receptors, act as positive allosteric modulat...