Apr 03 2026 This Week in Cardiology

John Mandrola offers an ACC recap of 5 big trials—Hi-PEITHO, PROTAVI, ORBITA-CTO, CHIPS-BCIS3 and CHAMPION AF This podcast is intended for healthcare professionals only . To read a partial transcript or to comment, visit: I Catheter Based Fibrinolysis of Pulmonary Embolism –Hi PEITHO Fibrinolysis Treatment Validated in Large Trial for Acute Intermediate-Risk PE Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism (HI PEITHO) National Early Warning Score (NEWS) II PRO-TAVI trial Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI) 10.1016/S0140-6736(26)00308-9 External Link PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation (Notion 3) III ORBITA CTO Sham vs PCI for Angina Relief Tightly Blinded Trial Confirms PCI Reduces Angina in Obstructive Occlusion A Randomized, Placebo-Controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention in Stable Angina - ORBITA-CTO ORBITA 1 10.1016/S0140-6736(17)32714-9 External Link ORBITA 2 DECISION CTO EuroCTO IV CHIPS BCIS3 Impella Supported High-Risk PCI Adoption Before Evidence: CHIP-BCIS3 Humbles Impella Left Ventricular Unloading in High-Risk PCI (CHIP BCIS3) Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock (DanGer Shock) V CHAMPION AF – Watchman vs DOAC in Patients With AF CHAMPION-AF Trial Finds LAAC an Alternative for NOAC in Lower-Risk Patients Six Reasons Why CHAMPION-AF Should Not Change Practice Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation (CHAMPION AF) Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation (CLOSURE AF) You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. Questions or feedback, please contact news@medscape.net

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Apr 03 2026 This Week in Cardiology is an episode from This Week in Cardiology by Medscape Podcasts.

This episode is 43:55 long.

This episode was published on Apr 3, 2026.

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