Ep. 303: “Organoid Models of Cancer” Featuring Dr. Alice Soragni

Guest: Dr. Alice Soragni is an Associate Professor at the University of California, Los Angeles. She talks about her work on patient-derived organoids and how they can be adapted for drug screening . She also discusses how she transitioned from structural biology to research on protein aggregation and rare diseases, and the current social media landscape for scientists. (45:20) Featured Products and Resources: Download a free wallchart on the applications of organoid cultures. Take your human pluripotent stem cell cultures further with mTeSR™ Plus. The Stem Cell Science Round Up Optogenetic Control of Morphogen Production – Researchers established a model that recapitulates Sonic hedgehog-mediated patterning of the vertebrate neural tube. (4:17) Oligodendrocyte Maturation – Reducing SOX6 levels unlocks oligodendrocyte maturation and myelination. (15:45) CAR T Therapy for Kidney Disease – Targeting extracellular matrix-producing cells with CAR T therapy is a therapeutic strategy for chronic kidney disease. (24:44) Lung Xenotransplantation – A lung from a gene-edited pig was transplanted into a brain-dead human recipient. (35:00)

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Ep. 303: “Organoid Models of Cancer” Featuring Dr. Alice Soragni is an episode from The Stem Cell Podcast by The Stem Cell Podcast.

This episode is 1:35:25 long.

This episode was published on Sep 2, 2025.

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