Episode 147: Genetic Mutation and Repair

Here we survey of the causes and consequences of genetic mutation, including a discussion of mechanisms of endogenous and induced mutations, rates of mutation, types of single nucleotide mutations, and the phenotypic effects of mutation. We also discuss various mechanisms for detecting and repairing genetic mutations, including base excision repair, DNA mismatch repair, nucleotide excision repair, double strand break repair. We conclude with an examination of large-scale chromosomal changes, including deletions, duplications, inversions, and translocations, unequal crossing over, with a brief look at polypoidy in plants and aneuploidy in humans. Recommended pre-listening is Episodes 34 and 35: DNA Structure and Function, and Episode 44: Cell Division. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter.

You can listen to Episode 147: Genetic Mutation and Repair online on Radio and Podcast. Open the player on this page to stream the available audio.

Episode 147: Genetic Mutation and Repair is an episode from The Science of Everything Podcast by James Fodor.

This episode is 73:51 long.

This episode was published on Aug 31, 2024.

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