Why Does Umami Taste So Good?
Today, we are rebooting an absolute classic from way back in our catalog - episode 9. Avi teaches us about the biology behind the taste of u...
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The Curious Clinicians is a medical podcast that asks "why?". Why do diseases present in certain ways? What are the mechanisms of treatments we use? Why does the human body function as it do...
Today, we are rebooting an absolute classic from way back in our catalog - episode 9. Avi teaches us about the biology behind the taste of u...
Why don't interstitial lung disease patients typically get increased pCO₂? The answer involves one of the fastest chemical reactions in the...
In this neck(st) episode, Avi asks an isthmus-ing question: Why does an autoimmune antibody stimulate the thyroid in Graves disease? Click h...
We apologize for the break in our regularly scheduled programming! This is a reboot of Episode 77, originally posted in September 2023, whic...
This is a reboot of Episode 66, originally posted back in March 2023, where investigated why tricuspid valve endocarditis is more common in...

This week, Tony shares a morning report physiology pearl: Why do patients with active lupus have a low CRP? Click here to obtain AMA PRA Cat...
Cold and flu season greetings from the Curious Clinicians! We hope you all are cold-free, but we were unfortunately under the weather this w...
This week, Hannah shares the story of an overlooked piece of the coagulation cascade, beginning with a 1950s medical mystery: Why didn't Joh...
This week, Avi shares the pathophysiology behind an important question: Why can't people with familial fatal insomnia fall asleep? Click her...
This week, Tony explores a fascinating, hospital rounds-ready question: Why does cirrhosis cause low SAAG ascites? You can read the show not...
This week, Avi follows up Episodes 112 and 114 with the question: How does a bacterial species called Deinococcus radiodurans withstand extr...
This week, Dr. Mike Todorovic returns as a special guest to tell us about his book with Dr. Matt Barton, The Body A-Z! Join us as Dr. Mike g...
This week, Tony brings us a question straight from the hospital wards: Why does valproic acid cause elevated ammonia? You can read the show...
This week, Dr. Mark Shapiro joins us for a candid conversation about the art of the question. Join us to think through how we interview, how...
This week, Avi follows up Episode 112 with the question: What's with the black mold growing inside Chernobyl? You can read the show notes he...
This week, we bring back a classic question for new interns and old hats alike: Why do we give calcium in hyperkalemia? You can read the sho...
This week, Tony poses a hard question: Why does calcium deposit in blood vessels? You can read the show notes here ! Click here to obtain AM...
This week, Avi asks: Why was iodine given to people exposed to radioactivity after Chernobyl? You can read the show notes here ! Click here...
This week, Tony asks a physiologic question: Why is Duffy Null status associated with lower neutrophil counts? You can read the show notes h...
This week, Avi shares a saline-ent question: Why does rubbing salt in a wound hurt so much? You can read the show notes here ! Click here to...
This week, Tony shares another "fresh case" physiology question: Why don't we all get spontaneous HIT? You can read the show notes here ! Cl...
This week, Avi shares new insights on the topic of episode 61: alpha-gal! We tackle the question: How could alpha-gal be used to treat cance...
This week, Hannah dives into a question inspired by nature: Why do humans have such a keen smell for the scent of the rain? You can read the...
This week, Tony brings us a fresh case straight from morning report! Join the Curious Clinicians as we learn: Why do patients with methemogl...
We're on a gram negative run! Join the Curious Clinicians as we learn: Why does Pseudomonas smell like grapes? Watch this episode on our new...
Producer Giancarlo Buonomo is back! Join the Curious Clinicians as we learn: Why do we worry about Pseudomonas infection in diabetic patient...
Welcome back to the Curious Clinicians! In today's episode, Tony asks an important question: "Why don't we administer insulin orally?" Read...
Happy Holidays from the Curious Clinicians! In today's episode, Avi shells us about a fascinating question: "Why do lobsters live so long?"...
In today's episode, Hannah asks the question: "Why do we 'automatically' form antibodies to ABO blood type antigens that are not our own?" R...
Join us as we revisit our annual Thanksgiving episode, in which we answered the question: "Does tryptophan in turkey really cause a food com...
For our 100th episode this week, the Curious Clinicians take a look back at some of our favorite old episodes. Take a trip down memory lane...
This week, the Curious Clinicians come to you LIVE from the CHEST 2024 conference explore a breathtaking topic: How could you live with only...
Before our 100th episode, we are rebooting some favorite early episodes! In episode 89, we asked the question: Why don't elephants get cance...
This week, the Curious Clinicians meet Dr. Jessi Gold to talk about an important, and often undiscussed question in medicine: "How Do You Fe...
This week, the Curious Clinicians explore the mechanism behind-- and against-- a common prescribing cascade: Why does gabapentin cause edema...
Before our 100th episode, we are rebooting some favorite early episodes! In episode 24, we asked the question: Why is fever beneficial? Read...
Before our 100th episode, we are rebooting some favorite early episodes! In episode 25, we asked the question: Why can furosemide improve pu...
Dr. Mike Todorovic, medical educator and science communicator extraordinaire, joins The Curious Clinicians to discuss the Na+/K+ ATPase pump...
This week, the Curious Clinicians return to the topic of episode 72, "Bringing up Beethoven" with a surprising news update and new perspecti...
This week, the Curious Clinicians give a 'hot take' on a common symptoms: why do hot flashes occur? Watch this episode on our new YouTube ch...
Producer Giancarlo Buonomo joins the Curious Clinicians this week to answer a morning report musing: why do we use IV PPIs to treat upper GI...
Instead of "Why do we...?" this week the Curious Clinicians answer a "Why don't we?" question: why don't we use steroids in acute pancreatit...
The Curious Clinicians answer a fascinating historical perspective: what was the role of antibiotics in ancient society ? Watch this episode...
The Curious Clinicians answer a sweet question about a new medication: Why do SGLT2 inhibitors cause erythrocytosis? Watch this episode on o...
The Curious Clinicians answer a gigantic oncologic and evolutionary question: Why don't elephants get (as much) cancer? Watch this episode o...
Hold your breath for this one! The Curious Clinicians answer a puzzling pulmonary physiology question: Why can systemic pulmonary vasodilato...
The Curious Clinicians answer an early curiosity question: Why do my fingers wrinkle when I take a bath? Watch this episode on our new YouTu...
In this episode from our archives, originally posted on September 16, 2020, The Curious Clinicians examined why the savory flavor umami is S...
The Curious Clinicians are on tap to ask, why does chronic alcohol use cause macrocytosis? Read the show notes here . Click here to obtain A...
Welcome to NephMadness 2024! In collaboration with Things We Do For No Reason (TWDFNR), we are excited to promote the start of this amazing...