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A collection of unhurried conversations with world-class thinkers, founders, and scientists.
I'm reposting my 2022 interview with Kevin Esvelt on the deranged USAID program "DEEP VZN," in conjunction with my latest appearance on Sam...
Might we unwittingly start sharing our world with a super AI? A monologue and (mostly) playful thought experiment.
Will the glittering dawn of the genai era be accompanied by a dark tsunami of pixel-perfect deep fakes? I discuss this prospect with Sam Har...
My thoughts on what's happening in the mad world of generative AI, announcing my new home online at robreid.substack.com, and more.
USAID's new "DEEP VZN" program aims to discover new pandemic-grade viruses, then broadcast their genomes to the world, according to MIT evol...
A wide-ranging discussion of cognition in octopuses & cuttlefish, plus many, many other topics with globally renowned sensory ecologist Roge...
Harvard epidemiologist Megan Murray tells us all about the anti-tuberculosis vaccine "BCG," and the astonishing protection it may provide ag...
This is closely tied to a 4-hour collaboration between Sam Harris and me, which Sam is posting to his podcast's feed. I strongly recommend t...
This "episode" is just a quick new announcement of a new season of the podcast (finally)! And also of something very cool that I'm working o...
Quantitative Psychologist Don Hoffman has a head-spinning take on the true nature of reality vs. what our senses report to us. This is a rev...
Quantum mechanics – and its eerie "Many Worlds" interpretation – are explored in terms that both poets & physicists can appreciate.
The baffling and fascinating mysteries connected to the phenomenon of consciousness are explored in this conversation with the deeply though...
This morning, TED posted a talk I just gave at their annual conference (on 11 days notice!). Kevin Rose interviewed me about my talk for his...
The drug known as Molly, Ecstasy and MDMA may soon get regulatory approved for therapeutic use, thanks to a 34-year campaign waged by Rick D...
The drug known as Molly, Ecstasy and MDMA may soon get regulatory approved for therapeutic use, thanks to a 34-year campaign waged by Rick D...
Stuart Russell's textbook is used to teach AI in over 1,400 universities and 120 countries. If AI scares him, it should scare you too.
The food allergy epidemic is mysterious, volatile, and growing fast. Kari Nadeau and her Stanford team are trying to halt it.
A rampage killer with a knife can kill a few. With a gun, dozens. With a jetliner, way more. What might future tech enable? In Part Two of o...
Naval & I discuss a horrifying risk. We questioned whether to post this. Might it give someone ideas? Well, the bad guys already HAVE ideas....
Not yet 40, Ed Boyden has already concocted a panoply of tools, which are revolutionizing neuroscience research. He tells us all about optog...
We start with a review of this podcast's 2019 roadmap. Then – recorded before a live audience in Gainesville, Florida – I'M the interviewee...
Both a recap and extensive update of last summer's conversation about neuroscience, consciousness, and the medical potential of video games.
Did the product of an alien intelligence make a near-Earth approach last fall? Harvard Astronomy Department Chair Avi Loeb believes this is...
Amazing work at Stanford could restore vision to the blind. Then later become a gateway some mind-blowing neural augmentation! We discuss th...
This spring, Yale evolutionary psychologist Laurie Santos debuted a course about happiness, almost as an experiment. It became the most popu...
Can humankind survive this century? Great Britain's Astronomer Royal Martin Rees shares some of his profoundly original thinking on this fra...
Dark matter, dark energy, and black holes are the universe's three most massive mysteries. Literally! Yale astrophysicist Priya Natarajan ta...
Andrew Youn's One Acre Found is bringing food security to hundreds of thousands of families throughout Central Africa. Now THAT'S an inspiri...
The genetic code of Neanderthals, archaic humans, and other elders is reconfiguring much of our understanding of human history. And it could...
A bold and brilliant refutation of the common wisdom about sexual attraction, aesthetics, and more. Rick Prum is an evolutionary heretic. An...
The full lowdown on where this podcast is going from here.
Floyd Romesberg added two letters to DNA's ancient four-letter alphabet. He got this running in cells. And coding proteins. His cell lines h...
Over six consecutive decades, Stewart Brand has impacted society, tech and science in outlandishly diverse ways. This truly unhurried conver...
An examination of the science of psychopathy from my buddy Jordan Harbinger's terrific podcast. This bonus episode is in addition to the two...
Key aspects of medical technology are improving even faster than computers. What are the ramifications for our health? For our lifespans? Dr...
The largest-ever clinical trial of a psychedelic drug will soon begin in Europe and North America. The drug is psilocybin - the active ingre...
Quantitative Psychologist Don Hoffman has a head-spinning take on the true nature of reality vs. what our senses report to us. Is it the mos...
In this very atypical episode, the tables turn and I'm the interviewee! We discuss all of my creative projects, including this podcast serie...
George Church helped found 22 companies, and co-invented the paradigm-shattering gene editing technique CRISPR. In our interview, he deliver...
Rodney Brooks is a founding luminary of TWO vital domains in tech: robotics and AI. He's the father of the Roomba, the long-time head of MIT...
Neuroscientist David Eagleman has done groundbreaking work on how we perceive time. Now he hopes to radically expand the pantheon of human s...
After stints at Google and Facebook, serial entrepreneur Mary Lou Jepsen is ready to upend the worlds of medical imaging and ... telepathy....
Aubrey de Grey is a highly credentialed scientist who believes it's within our grasp to REVERSE human aging in the next few decades. Dozens...
A wide-ranging set of excerpts from the After On audiobook, read brilliant folks including John Hodgman, Felicia Day, Jesse Cox, Tom Merritt...
This week, Broadway's own January LaVoy and legendary fantasy writer Patrick Rothfuss read/perform the the opening of the After On audiobook...
Whether you're a cryptocurrency novice or expert, this episode will teach you a ton. My guest, Fred Ehrsam, founded the world's largest plat...
You will soon have access to a dizzying battery of facts about your health. Some could be horrid or positive on a life-changing scale! But m...
A vast alien civilization is so into American pop music, it recently committed the biggest copyright violation since the dawn of time. Again...
Andy McAfee of MIT is a leading thinker about how robotics and other automation will influence the future of work and jobs. We touch on some...
Ev Williams co-founded and ran both Twitter and Blogger.com, and is now the founder/CEO of Medium. He's a deep thinker about ideas morph & t...