#553: All of our tools
This episode is a fun crossover from our Python news and tips podcast, Python Bytes. We have had some big changes over there. Brian Okken ha...
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Talk Python To Me - Python conversations for passionate developers
Talk Python to Me is a weekly podcast hosted by Michael Kennedy. The show covers a wide array of Python topics as well as many related topics (e.g. MongoDB, AngularJS, DevOps).The format is...
Talk Python To Me - Python conversations for passionate developers Podcast Guide
Listen to Talk Python To Me - Python conversations for passionate developers, a Technology podcast by Michael Kennedy. Stream 552 episodes in English, follow new audio stories, and play episodes online on Radio and Podcast.
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20 of 552 episodes#552: Astral joins OpenAI
OpenAI just acquired Astral, the company behind uv, Ruff, and ty. And if your first thought was "wait, is uv toast?", you are not alone. But...
#551: Stroll Down Startup Lane - 2026
If you've ever been to PyCon, you know one of the best parts of the expo hall is Startup Row, a stretch of booths where early-stage companie...
#550: AI Contributions and Maintainer Load in Open Source
You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your open source project. Thirteen thousand lines added....
#549: Great Docs
Your documentation has two audiences now - humans reading the rendered HTML, and AI agents trying to make sense of your library. Rich Iannon...
#548: Event Sourcing Design Pattern
What if your database worked more like Git? Every change captured as an immutable event you can replay, instead of a single mutating row tha...
#547: Parallel Python at Anyscale with Ray
When OpenAI trained GPT-3, they didn't roll their own orchestration layer. They used Ray, an open source Python framework born out of the sa...
#546: Self hosting apps for Python people
The cloud is convenient until it isn't. You upload your photos, sync your contacts, click through the cookie banners. Then prices go up agai...
#545: OWASP Top 10 (2025 List) for Python Devs
The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Ta...
#544: Wheel Next + Packaging PEPs
When you pip install a package with compiled code, the wheel you get is built for CPU features from 2009. Want newer optimizations like AVX2...
#543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate
When you type a question into ChatGPT, the model only has what you typed to work with. But tools like Claude Code can plan, iterate, test, a...
#542: Zensical - a modern static site generator
If you've built documentation in the Python ecosystem, chances are you've used Martin Donath's work. His Material for MKDocs powers docs for...
#541: Monty - Python in Rust for AI
When LLMs write code to accomplish a task, that code has to actually run somewhere. And right now, the options aren't great. Spin up a sandb...
#540: Modern Python monorepo with uv and prek
Monorepos -- you've heard the talks, you've read the blog posts, maybe you've seen a few tantalizing glimpses into how Google or Meta organi...
#539: Catching up with the Python Typing Council
You're adding type hints to your Python code, your editor is happy, autocomplete is working great. But then you switch tools and suddenly th...
#538: Python in Digital Humanities
Digital humanities sounds niche, until you realize it can mean a searchable archive of U.S. amendment proposals, Irish folklore, or pigment...
#537: Datastar: Modern web dev, simplified
You love building web apps with Python, and HTMX got you excited about the hypermedia approach -- let the server drive the HTML, skip the Ja...
#536: Fly inside FastAPI Cloud
You've built your FastAPI app, it's running great locally, and now you want to share it with the world. But then reality hits -- containers,...
#535: PyView: Real-time Python Web Apps
Building on the web is like working with the perfect clay. It’s malleable and can become almost anything. But too often, frameworks try to h...
#534: diskcache: Your secret Python perf weapon
Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache bu...