991: Pair Programming with AI in Your Python Notebook, with Dr. Trevor Manz

Dr. Trevor Manz of Marimo talks to Jon Krohn about Marimo Pair, an open-source agent skill that teaches coding agents like Claude Code how to drive a reactive Python notebook, reading cell state, running Python in the kernel, taking screenshots of cells, and iterating on data tasks the way agents iterate on traditional software. Trevor also unpacks recursive language models, his AnyWidget project that bridges Python and the web, and his journey from a Wisconsin small town and Harvard bioinformatics research to founding-engineer life at Marimo. Listen to the episode to hear why no matter where AI takes us, curiosity and going deep on a topic will always be valuable. Additional materials: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Interested in sponsoring a SuperDataScience Podcast episode? Email natalie@superdatascience.com for sponsorship information. In this episode you will learn: (07:04) What Marimo Pair is and how it teaches agents to use notebooks as a tool (13:03) How agent skills work as folders of markdown files (24:15) Trevor's day-to-day workflow combining Claude Code and Marimo Pair (31:51) Recursive language models and why they could be the future of agentic reasoning (57:33) Career advice on curiosity, going deep, and becoming a domain expert

You can listen to 991: Pair Programming with AI in Your Python Notebook, with Dr. Trevor Manz online on Radio and Podcast. Open the player on this page to stream the available audio.

991: Pair Programming with AI in Your Python Notebook, with Dr. Trevor Manz is an episode from SuperDataScience by Jon Krohn.

This episode is 68:51 long.

This episode was published on May 12, 2026.

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