
357 | Jeff Coller on mRNA, Vaccines, and Bespoke Therapeutics
Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between t...
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Messenger RNA (mRNA) plays a literally central role in the functioning of life as we know it, shuttling information back and forth between t...

All ideas have a history, no matter how inevitable and well-entrenched they may seem to us today. The later Enlightenment was a heady time w...

Welcome to the June 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the o...

One of the major obstacles to understanding quantum mechanics is the difficulty we have in simply accepting what the theory itself is tellin...

Did I have any freedom in choosing this particular podcast guest? At the level of particles, fields, and the fundamental laws of physics; no...

Economic markets are efficient ways of deciding fair prices, at least in ideal circumstances of perfect competition, information, and choice...

Welcome to the May 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the on...

The connectome is the wiring diagram of a brain, a big matrix that tells us what neurons talk to what other neurons. Understanding it is an...

Peter Singer has been an influential philosopher for a number of decades. He was a significant early voice in animal rights, has been a lead...

We are more familiar with ourselves than with anything else in the universe, but we generally don't come very close to really understanding...

Welcome to the April 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the...

There is something special about gravity. After decades of effort, there is still no convergence on the right way to reconcile Einstein's th...

"Lamarkism" is a term often attached to a seemingly discredited idea in evolutionary biology: that one organism could acquire characteristic...

In the 18th century, philosopher Jeremy Bentham suggested the Panopticon as a model of a prison where inmates could be constantly observed b...

Intelligence is a many splendored thing, especially when it comes to comparisons between species. Chimpanzees are better than humans at some...

Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the...

Behaving rationally involves facing up to conditions of uncertainty; we never navigate the world with perfect confidence. Sometimes we are u...

It's possible to look at the course of history over the past few centuries and discern a movement toward increasing democracy, freedom, and...

For all that human beings spend a lot of their time thinking, it's far from obvious what that process actually entails. Part of it amounts t...

Welcome to the February 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also t...