
Clozapine Monitoring: New Guidelines for the Post-REMS Era
In this episode, we explore new international guidelines for clozapine monitoring following the FDA's REMS rescission. Should patients on st...
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Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and...

In this episode, we explore new international guidelines for clozapine monitoring following the FDA's REMS rescission. Should patients on st...

In this episode, we explore how pregnancy reshapes the pharmacokinetics of psychiatric medications — and what that means for your patients....

In this episode, we explore bright light therapy (BLT) as a powerful adjunctive treatment for bipolar depression — examining the neuroscienc...

In this episode, we explore three often-overlooked side effects of lithium — sexual dysfunction, hair loss, and skin changes like acne and p...

In this episode, we explore KarXT, a newly FDA-approved antipsychotic with a groundbreaking cholinergic mechanism, through the lens of a sin...

In this episode, we explore how to keep your patients on lithium by getting ahead of two of its most common challenges — weight gain and gas...

In this episode, we explore a surprising new contender in the fight against alcohol use disorder — semaglutide. Could the blockbuster weight...

In this episode, we explore lithium's renal side effects with Dr. David Osser from Harvard Medical School. How can we keep patients safe whi...

In this episode, we explore cariprazine's efficacy and safety in older adults with bipolar I disorder. Does age change how we should dose th...

In this episode, we explore essential baseline testing, monitoring protocols, and optimal dosing strategies for lithium with Dr. David Osser...

In this episode, we explore the delicate balance of prescribing stimulants for adult ADHD when abuse potential is a concern. How do you dist...

In this episode, we explore groundbreaking research on treating cannabis-induced psychosis with antipsychotic medications. Which formulation...

In this episode, we explore stimulant medications for adult ADHD with Dr. Oscar Bukstein. Why have amphetamines overtaken methylphenidate as...

In this episode, we explore the groundbreaking COaST trial examining semaglutide for clozapine-induced weight gain in schizophrenia patients...

In this episode, we explore the treatment algorithm for adult ADHD with Dr. Oscar Bukstein from Harvard Medical School. Should you start wit...

In this episode, we explore pramipexole—a Parkinson's medication—as a promising add-on treatment for treatment-resistant bipolar depression....

In this episode, we explore the controversial role of SERT gene testing in predicting SSRI response with Dr. Chris Aiken. Can genetic testin...

In this episode, we explore a critical drug interaction: SSRIs combined with anticoagulants increase major bleeding risk by 35-47%. Should a...

In this episode, we explore the paradox of pharmacogenetic testing with Dr. Chris Aiken: why do these tests consistently fail in clinical tr...

In this episode, we explore how Lurasidone at lower doses (20-60 mg/day) effectively treats both depression and anxiety in bipolar I disorde...

In this episode, we explore how GLP-1 agonists—the weight loss medications making headlines everywhere—could revolutionize management of ant...

In this episode, we explore pharmacogenetics-guided dosing strategies with Dr. Chris Aiken. What if your patient's treatment failure isn't a...

In this episode, we explore the newly published INTEGRATE guidelines—the first truly international algorithm for schizophrenia treatment. Sh...

In this episode, we explore the practical role of genetic testing in psychiatry with Dr. Chris Aiken. Which genetic tests actually matter in...

In this episode, we explore a head-to-head comparison of lithium versus quetiapine augmentation for treatment-resistant depression. When pat...

In this episode, we explore pharmacologic strategies for postpartum psychosis with insights from Dr. Lauren Osborne, focusing on a critical...

In this episode, we explore brexanolone and zuranolone—the first FDA-approved medications specifically for postpartum depression. How do the...

In this episode, we explore lumateperone for treating major depressive episodes with mixed features – that challenging presentation where pa...

In this episode, we explore pharmacologic treatment for postpartum depression in breastfeeding mothers. Can psychiatric medications be safel...

In this episode, we explore a new study examining whether antidepressants and antipsychotics truly increase the risk of torsades de pointes,...

In this episode, we explore the critical distinction between postpartum OCD and postpartum psychosis. Dr. Lauren Osborne reveals why accurat...

In this episode, we examine groundbreaking research that challenges the widespread clinical belief that SSRI side effects improve with time....

In this episode, we explore evidence-based strategies for augmenting lithium when monotherapy fails in acute mania. Why is quetiapine the pr...

In this episode, we explore a groundbreaking Mayo Clinic algorithm that revolutionizes antipsychotic selection for first-episode psychosis....

In this episode, we challenge conventional prescribing by exploring why lithium should be the first-line treatment for acute classic mania,...

In this episode, we explore a head-to-head comparison of trazodone, doxepin, and melatonin for treating insomnia when benzodiazepines are of...

In this episode, we explore the critical decision of when to add lithium or valproate to second-generation antipsychotics in mixed manic epi...

In this episode, we explore a provocative argument for reconsidering disulfiram as a first-line treatment for alcohol use disorder. Could th...

In this episode, we explore the complex pharmacological management of mixed mania, a challenging bipolar presentation affecting up to 40% of...

In this episode, we explore psychedelic-assisted therapy in clinical practice, examining how these treatments differ fundamentally from trad...

In this episode, we explore groundbreaking research revealing that lower doses of lurasidone (40-60mg) may be more effective for bipolar dep...

In this episode, we explore a compelling comparison between olanzapine and risperidone for managing behavioral symptoms in dementia patients...

In this episode, we explore the complex drug-drug interactions between psychedelics and psychiatric medications. Do SSRIs really blunt psych...

In this episode, we challenge the conventional wisdom of "what gets them well keeps them well" by exploring groundbreaking Finnish research...

In this episode, we explore how psychedelics like psilocybin disrupt the brain's default mode network, creating windows of neuroplasticity t...

In this episode, we explore groundbreaking research showing how long-acting injectable antipsychotics can literally save lives in schizophre...

In this episode, we explore the fascinating mechanisms behind psychedelic drugs in psychiatry, examining how substances like psilocybin and...

In this episode, we explore groundbreaking research comparing weight gain across eight common antidepressants. Using data from 183,000 patie...

In this episode, we explore lisdexamfetamine as the first FDA-approved medication for binge eating disorder. Can one medication effectively...

In this episode, we explore groundbreaking Swedish research on GLP-1 receptor agonists as a potential new treatment for alcohol use disorder...