Deprescribing Benzodiazepines: When Tapering Might Do More Harm Than Good
In this episode, we explore the nuanced landscape of benzodiazepine tapering, guided by a major 2024 joint clinical practice guideline. Are...
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Psychopharmacology and Psychiatry Updates
Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from CME presentations. Practical and...
Psychopharmacology and Psychiatry Updates Podcast Guide
Listen to Psychopharmacology and Psychiatry Updates, a Health podcast by Psychopharmacology Institute. Stream 122 episodes in English, follow new audio stories, and play episodes online on Radio and Podcast.
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20 of 122 episodesDisulfiram Unpacked: Efficacy, Risks, and Liver Safety
In this episode, we explore disulfiram (Antabuse), one of the oldest FDA-approved treatments for alcohol use disorder. Dr. Kevin Sevarino br...
GLP-1s and Lithium: What Clinicians Need to Know
In this episode, we explore a surprising drug interaction that every lithium-prescribing clinician should know about: can semaglutide, the w...
Naltrexone for Alcohol Use Disorder: What You Should Know
In this episode, we explore how naltrexone — the most widely used medication for alcohol use disorder in the US — works, how to dose it safe...
The OPTIMUM Trial: A Roadmap for Treatment-Resistant Depression in Late Life
In this episode, we explore the OPTIMUM trial, a landmark study examining how to treat older adults with treatment-resistant depression when...
Difficult-to-Treat Depression: First, Second, and Third-Line Strategies
In this episode, we explore what to do when antidepressants aren't working. How do you systematically approach a patient who isn't getting b...
Is High-Dose Olanzapine A Clozapine Alternative?
In this episode, we explore whether high-dose olanzapine — beyond the FDA-approved 20 mg ceiling — can be a viable strategy for patients wit...
CANMAT Guidelines: Herbs, Supplements, and Depression
In this episode, we explore what the CANMAT guidelines say about complementary and alternative medicine (CAM) for depression — from St. John...
Xylazine in the ED: Managing Toxicity
In this episode, we explore the growing threat of xylazine — a veterinary sedative increasingly found in illicit drug supplies — and what cl...
Choosing the First Step in Depression Treatment: A CANMAT Guide
In this episode, we explore how to select the right initial treatment for depression using the updated CANMAT guidelines. How do severity, p...
After Delirium Clears: When to Deprescribe?
In this episode, we explore the hidden dangers of leaving antipsychotics running long after a hospital delirium episode has resolved. Could...
The Clinician's Guide to Paliperidone & Risperidone LAIs
In this episode, we explore the practical dosing, initiation, and conversion strategies for paliperidone palmitate and risperidone long-acti...
Antipsychotic Switching: Six Clinical Tips
In this episode, we explore the surprisingly thin evidence base behind antipsychotic switching — one of psychiatry's most common clinical ma...
Mastering Long-Acting Injectables: Aripiprazole & Olanzapine
In this episode, we explore the practical use of long-acting injectable antipsychotics in schizophrenia — specifically aripiprazole and olan...
Predicting Lithium Response in Bipolar Disorder
In this episode, we explore whether we can predict which bipolar disorder treatments will work for specific patients before months of trial...
Preventing Relapse: The Role of LAIs in Schizophrenia
In this episode, we explore when and why long-acting injectable antipsychotics (LAIs) should be considered for patients with schizophrenia,...
Could Lithium Play a Role in Preventing Alzheimer's Disease?
In this episode, we explore a striking new Nature study suggesting that lithium deficiency may play a central role in the onset of Alzheimer...
Managing ADHD in Pregnancy: Weighing Risk versus Risk
In this episode, we explore the nuanced challenge of managing ADHD with stimulant medications during pregnancy. Is stopping the medication a...
Ondansetron for Negative Symptoms of Schizophrenia
In this episode, we examine a surprising repurposing of ondansetron — a common antiemetic — as a potential adjunctive treatment for the noto...
Managing SSRIs During Pregnancy: Myths vs. Evidence
In this episode, we explore how to manage SSRI treatment in pregnant patients — addressing common fears around fetal malformations, medicati...