EP 149: The Placebo-Controlled Revolution: Redefining Evidence in Device Trials

In this week's episode of Parallax, Dr Ankur Kalra welcomes Prof Rasha Al-Lamee, interventional cardiology consultant and professor of medicine/cardiology at Imperial College London, and deputy editor of JACC. Prof Al-Lamee has transformed interventional cardiology through her pioneering work on the ORBITA trial series and coronary sinus reducer device studies, introducing the paradigm-shifting concept of sham-controlled device trials to the field. What makes a clinical assumption worth questioning? How do we design trials that reveal truth rather than confirm bias? When does revascularization truly benefit patients with stable angina? Questions and comments can be sent to "podcast@radcliffe-group.com" and may be answered by Ankur in the next episode. Guest: @RashaAlLameeMD Host: @AnkurKalraMD and produced by: @RadcliffeCardio Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.

You can listen to EP 149: The Placebo-Controlled Revolution: Redefining Evidence in Device Trials online on Radio and Podcast. Open the player on this page to stream the available audio.

EP 149: The Placebo-Controlled Revolution: Redefining Evidence in Device Trials is an episode from Parallax by Ankur Kalra by Parallax by Ankur Kalra.

This episode is 00:33:07 long.

This episode was published on Dec 22, 2025.

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