Jeff Sperry - Safer, earlier.

One minor clarification Jeff asked me to make - at around 7:15 he mentions that Vertex does not do any commercial manufacturing in-house. Vertex does not perform in-house, commercial scale production of drug substances. You will hear the following terms used during the interview. I’ve included some descriptions and links to deeper reading. Vertex - Vertex Pharmaceuticals - Exotherm – An exothermic reaction is one that gives off heat. The phrase exotherm is often used as a shortened form of ‘exothermic reaction’. Unwanted exotherms in process safety cause a potential safety hazard, as they can potentially heat a reaction, beyond the safe limits of available cooling. DSC – Differential Scanning Calorimetry (DSC) is a technique for thermal analysis, in which, the difference in the amount of heat required to increased the temperature of a sample is measured as a function of temperature. It can be used to determine a number of properties of a sample. TSU – The Thermal Screening Unit ( TSU ) is a system used to screen materials for potential hazards associated with heating. ARC – Accelerating Rate Calorimeter (ARC) is a system used to measure heat generating characteristics of reactions, or reaction components at a range to temperatures.Other reaction data can be determined with this tool GLP Tox Lot. - A Good Laboratory Toxicology lot is a batch of a drug, or drug like material prepared during drug development with the intention of testing safety (and other) properties. API – The Active Pharmaceutical Ingredient (API) is the drug element of a medicine. The drug would be, for example, diluted down with saline solution to make a medicine ready for injection. Buller Empowerment - Taylor Howard – As Jeff mentioned, he follows Taylor on LinkedIn – she’s at If you want to connect with Jeff, or find out more about his lab, you can find: On LinkedIn, Jeff can be found at On Twitter, Jeff goes by @SafeChem79 - Our theme music is "Wholesome" by Kevin MacLeod ( Music from License: CC BY ( ) Connect with me (Paul) at H.E.L. group can be found at online, on LinkedIn at on twitter we’re @hel_group, or search for us on Facebook

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Jeff Sperry - Safer, earlier. is an episode from Modern Chemistry Podcast by Paul Orange Ph.D..

This episode is 00:30:33 long.

This episode was published on Jun 18, 2020.

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