He won a Nobel here for AlphaFold. Then he left. - John Jumper
This episode is sponsored by Notion. Learn more about Notion's Developer Platform today at https://notion.com/mlstProtein folding stalled bi...
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Machine Learning Street Talk
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Machine Learning Street Talk Podcast Guide
Listen to Machine Learning Street Talk, a Technology podcast by Machine Learning Street Talk (MLST). Stream 253 episodes in English, follow new audio stories, and play episodes online on Radio and Podcast.
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When AI Decides You're a Threat — Brad Carson
Brad Carson was the Army's General Counsel, served two terms in Congress and was Acting Under Secretary of Defense for Personnel and Readine...
Intelligence is collective, not artificial — Prof. Michael I. Jordan (UC Berkeley / Inria)
Michael I. Jordan, described by Science magazine as the most influential computer scientist alive, has never thought of himself as an AI res...
The AI Models Smart Enough to Know They're Cheating — Beth Barnes & David Rein [METR]
Beth Barnes and David Rein on the one graph that ate the AI timelines discourse, and why the two people who built it are the most careful ab...
When AI Discovers The Next Transformer - Robert Lange (Sakana)
Robert Lange, founding researcher at Sakana AI, joins Tim to discuss *Shinka Evolve* — a framework that combines LLMs with evolutionary algo...
"Vibe Coding is a Slot Machine" - Jeremy Howard
Dive into the realities of AI-assisted coding, the origins of modern fine-tuning, and the cognitive science behind machine learning with fas...
Evolution "Doesn't Need" Mutation - Blaise Agüera y Arcas
What if life itself is just a really sophisticated computer program that wrote itself into existence? Blaise Agüera y Arcas presenting at AL...
VAEs Are Energy-Based Models? [Dr. Jeff Beck]
What makes something truly *intelligent?* Is a rock an agent? Could a perfect simulation of your brain actually *be* you? In this fascinatin...
Abstraction & Idealization: AI's Plato Problem [Mazviita Chirimuuta]
Professor Mazviita Chirimuuta joins us for a fascinating deep dive into the philosophy of neuroscience and what it really means to understan...
Why Every Brain Metaphor in History Has Been Wrong [SPECIAL EDITION]
What if everything we think we know about the brain is just a really good metaphor that we forgot was a metaphor?This episode takes you on a...
Bayesian Brain, Scientific Method, and Models [Dr. Jeff Beck]
Dr. Jeff Beck, mathematician turned computational neuroscientist, joins us for a fascinating deep dive into why the future of AI might look...
Your Brain is Running a Simulation Right Now [Max Bennett]
Tim sits down with Max Bennett to explore how our brains evolved over 600 million years—and what that means for understanding both human int...
The 3 Laws of Knowledge [César Hidalgo]
César Hidalgo has spent years trying to answer a deceptively simple question: What is knowledge, and why is it so hard to move around? We al...
"I Desperately Want To Live In The Matrix" - Dr. Mike Israetel
This is a lively, no-holds-barred debate about whether AI can truly be intelligent, conscious, or understand anything at all — and what happ...
Making deep learning perform real algorithms with Category Theory (Andrew Dudzik, Petar Velichkovich, Taco Cohen, Bruno Gavranović, Paul Lessard)
We often think of Large Language Models (LLMs) as all-knowing, but as the team reveals, they still struggle with the logic of a second-grade...
Are AI Benchmarks Telling The Full Story? [SPONSORED] (Andrew Gordon and Nora Petrova - Prolific)
Is a car that wins a Formula 1 race the best choice for your morning commute? Probably not. In this sponsored deep dive with Prolific, we ex...
The Mathematical Foundations of Intelligence [Professor Yi Ma]
What if everything we think we know about AI understanding is wrong? Is compression the key to intelligence? Or is there something more—a le...
Pedro Domingos: Tensor Logic Unifies AI Paradigms
Pedro Domingos, author of the bestselling book "The Master Algorithm," introduces his latest work: Tensor Logic - a new programming language...
He Co-Invented the Transformer. Now: Continuous Thought Machines - Llion Jones and Luke Darlow [Sakana AI]
The Transformer architecture (which powers ChatGPT and nearly all modern AI) might be trapping the industry in a localized rut, preventing u...
Why Humans Are Still Powering AI [Sponsored]
Ever wonder where AI models actually get their "intelligence"? We reveal the dirty secret of Silicon Valley: behind every impressive AI syst...