Assessing enrichment, consolidating animal research guidance and understanding mouse aggression
February 2023 The papers behind the pod: Hobbiesiefken U et al . (2023). Rating enrichment items by female group-housed laboratory mice in m...
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LabAnimal
Behind the scenes with the authors and experts shaping in vivo science, technology and policy
Episodes
20 of 64 episodesReplacing animal-derived reagents, simulating in utero microinjections and clicker training for mouse gait assessment
January 2023 The papers behind the pod: Cassotta M et al . (2022). A worldwide survey on the use of animal-derived materials and reagents in...
Kidney organoid vascularisation, implementing masking and quantitatively assessing experiment severity
December 2022 The papers behind the pod: Menéndez ABC et al . (2022). Creating a kidney organoid-vasculature interaction model using a novel...
Assessing pain, living systematic reviews and inducing focal hypoxia in human neurons
November 2022 The papers behind the pod: Aulehner K et al . (2022). Grimace scale, burrowing, and nest building for the assessment of post-s...
Statistical planning, human cell cultures for toxoplasma and preventing boredom in laboratory rodents
October 2022 The papers behind the pod: Piper, SK et al. (2022). Statistical review of animal trials—A guideline. Biometrical Journal https:...
Larger species refinement special: improving the welfare of rabbits, non-human primates and sheep
September 2022 The papers behind the pod: Pinho RH et al. (2022). Validation of the rabbit pain behaviour scale (RPBS) to assess acute posto...
Better behavioural research, imaging with microbots and how housing density affects mouse microbiomes
August 2022 The papers behind the pod: Arjmand S et al. (2022). Tips and traps for behavioural animal experimentation. Acta Neuropsychiatric...
3Rs Prize: A benchtop organ-on-a-chip fabrication method and an ex vivo model of focal demyelination
July 2022 The papers behind the pod: Ferreira DA et al . (2021). Alternative to Soft Lithography for the Fabrication of Organ-on-a-Chip Elas...
Humane intervention points, virtual gene knockout and ex vivo brain slices for Parkinson's research
June 2022 The papers behind the pod: Williams WO and Baneux P (2022). Humane Intervention Points: Refining endpoint terminology to incorpora...
Microbrains for neurotoxicity testing, improved experimental design, and post-op severity assessment
May 2022 The papers behind the pod: Wang, Q et al. (2022). Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neuroto...
How environment and experimenter affect reproducibility, ex vivo adipocytes, and rodent enrichment
April 2022 The papers behind the pod: Nigri M et al. (2022). Role of Environment and Experimenter in Reproducibility of Behavioral Studies W...
Replacement methods for drug development, toxicology testing and cardiovascular research
The papers behind the pod: 1. Baran SW et al. (2022). Perspectives on the Evaluation and Adoption of Complex In Vitro Models in Drug Develop...
Issues with conventional rodent housing, playpens for rats, and using sleep to assess welfare
February https://doi.org/10.1186/s12915-021-01184-0 https://doi.org/10.1177/00236772211065920 https://doi.org/10.1038/s41598-021-04502-2 It’...
Reproducibility in cancer biology, training rats for refined fMRI, and playpens for mice
The papers behind the pod: 1. https://doi.org/10.7554/eLife.71601 & https://doi.org/10.7554/eLife.67995 2. https://doi.org/10.3389/fnins.202...
Refining anaesthesia and euthanasia for zebrafish and mice
Sedation is necessary for zebrafish during procedures such as imaging, biopsy, and surgery to ensure animal welfare and high-quality science...
Discover the winners of this year's Global AAALAC/IQ Awards
The papers behind the pod: 1. A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates. npj Vaccines...
People and strategies behind 3Rs science: compassion fatigue, culture of care and systematic reviews
The papers behind the pod: 1. Professional Quality of Life in Research Involving Laboratory Animals. Animals 11(9), 2639 (2021) https://doi....
3 Minute 3Rs September 2021
Sept 2021 You’re listening to the September episode of 3 Minute 3Rs. The papers behind the pod: Performance of preclinical models in predict...
3 Minute 3Rs August 2021
You’re listening to the August episode of 3 Minute 3Rs! The papers behind the pod: Refinement of the spinal cord injury rat model and valida...
3 Minute 3Rs July 2021
It’s the 3rd Thursday of July and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of...