Who Benefits Most from Brain Training and Exercise in Progressive MS

People with progressive multiple sclerosis often experience slowed cognitive processing speed. Researchers from Kessler Foundation analyzed data from the international CogEx trial, involving over 300 participants using brain training and exercise over 12 weeks. They found that improvement in cognitive speed varied, with better memory and higher pre-symptom IQ predicting greater gains. Factors like age, gender, or disability status did not affect outcomes. These findings highlight the need for personalized rehabilitation tailored to individuals’ cognitive profiles, moving beyond one-size-fits-all treatments. ===================================================================================== Kessler Foundation Investigators: Lead: Brian Sandroff, PhD ===================================================================================== READ this journal article: “Correlates of Processing Speed Change With Combined Cognitive Rehabilitation and Exercise in Progressive MS: Secondary Analysis of the CogEx Trial,” was published in Neurorehabilitation & Neural Repair (2025), PARTICIPATE: Interested in participating in our research remotely or in-person? Go to LISTEN to more Real-Life Science Summaries: This Real-Life Science summary is part of our series that translates peer-reviewed research into practical, real-world understanding. ===================================================================================== LOOKING FOR MORE PODCASTS? Join our listeners in 90 countries who enjoy learning about the work of Kessler Foundation.

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Who Benefits Most from Brain Training and Exercise in Progressive MS is an episode from Kessler Foundation Disability Rehabilitation Research and Employment by Kessler Foundation.

This episode is 00:03:58 long.

This episode was published on Feb 26, 2026.

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