Hepatitis B: Global Insights on Transmission and Treatment
Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lo...
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Author interviews that explore the latest clinical reviews.
Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lo...
Heart failure (HF) affects more than 64 million individuals worldwide, and 20% to 30% of patients with HF and systolic dysfunction have card...
In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and o...
Endometrial cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. Author Karen McLean, MD,...
Explore evidence-based clinical signs, diagnostic accuracy, and practical assessment strategies to optimize care with an in-depth look at th...
Absolute iron deficiency with or without anemia affects about 2 billion people worldwide and 14% of adults in the US. Discover causes, diagn...
Interview with Thomas Ibounig, MD, author of Incidental Rotator Cuff Abnormalities on Magnetic Resonance Imaging and Brian T. Feeley, MD, au...
Resistant hypertension affects about 10% of those treated for hypertension. Managing it involves lowering sodium intake, exercising, losing...
Peanut allergy affects about 2% of people in the US and most commonly develops in early childhood. Peanut introduction during infancy has le...
Overweight and obesity may cause 10% of new cancer diagnoses annually in the US. In this JAMA Review in the Translational Science series, au...
Chronic noninfectious diarrhea affects approximately 6% to 7% of adults in the US and significantly impairs quality of life. Author William...
Accurate assessment of intravascular volume facilitates decisions about fluid management in patients with volume overload. Author Edmund A....
Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the Univers...
Mark Cuban, entrepreneur, investor, and cofounder of the Mark Cuban Cost Plus Drug Company, joins JAMA Editor in Chief Kirsten Bibbins-Domin...
Opioid use disorder is the third most prevalent substance use disorder worldwide. Author Alexander Walley, MB, MSc, of Boston Medical Center...
Ovarian cancer may be prevented with removal of the fallopian tubes during pelvic or select abdominal surgery in eligible women. This proced...
IgA nephropathy is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, which often causes ki...
Restless legs syndrome is a sleep-related neurologic disorder that causes an overwhelming urge to move the limbs, which can cause substantia...
Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and...
Incidence rates of gastric cancer in younger individuals are on the rise and gastric cancer is the fifth-leading cause of cancer-related dea...
JAMA Deputy Editor Mary McDermott, MD, and JAMA Deputy Editor Kristin Walter, MD, MS, highlight their selections of top JAMA Clinical Review...
In this episode, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Medical News Director Jennifer Abbasi discuss the journal's...
Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease. WHO...
Head and neck cancer is the seventh most common cancer worldwide and is commonly associated with tobacco and alcohol use, or human papilloma...
Allergic rhinitis affects about 1 in 6 US adults. A recent JAMA Insights summarizes evidence regarding the associations of climate change an...
Clinicians should weigh benefits against risks when engaging patients in informed discussions about cannabis or cannabinoid use. Kevin Hill,...
Peripheral neuropathy affects approximately 1% of adults worldwide and can be associated with significant disability. Author Michelle Mauerm...
Metabolic dysfunction-associated steatotic liver disease (MASLD), an increasingly prevalent condition among adults worldwide, is associated...
The JAMA Summit on Firearm Violence convened 60 thought leaders from a wide array of disciplines to chart a roadmap that could lead to subst...
Keratinocyte carcinomas, which include basal cell carcinoma and squamous cell carcinoma, are common forms of skin cancer. Approximately 5.4...
Lung cancer in nonsmoking individuals is increasing worldwide and currently accounts for 15% to 20% of lung cancer cases globally. Benjamin...
Syphilis infections have increased in the US and worldwide over the past decade. Left untreated, syphilis can cause blindness, deafness, psy...
Microplastics, defined as plastics smaller than 5 mm, have been detected in human tissues at increasing rates and are associated with potent...
Severe refractory asthma, which affects approximately 1% to 5% of patients with asthma, is associated with increased morbidity and mortality...
Epidemiologist Brian Lee, PhD, discusses his study on acetaminophen use during pregnancy and children's risk of autism and other neurodevelo...
Health care professionals often use numbers to guide decisions, monitor patient health, and communicate information. Author Angela Fagerlin,...
Superficial vein thrombosis (SuVT) is characterized by thrombus formation in the superficial veins, typically in the lower or upper extremit...
Untreated hypothyroidism can cause serious health complications such as heart failure and myxedema coma. Author Maria Papaleontiou, MD, of t...
Interview with Alexander Chern, MD, author of Over-the-Counter Hearing Aid–Enabled Earbuds—Merging Hearing Health and Technology. Hosted by...
The incidence and prevalence of cutaneous melanoma in the US and worldwide have increased over the last 5 decades. JAMA Review Author John K...
Hemorrhoidal disease, pathology of the tissue lining the anal canal, affects approximately 10 million individuals in the US. Author Jean H....

Dalbavancin, a long-acting IV lipoglycopeptide, may be an option for the treatment of complicated Staphylococcus aureus bacteremia without r...
Prostatitis affects approximately 9.3% of men in their lifetime and includes acute and chronic bacterial infection and nonbacterial chronic...
Geroscience aims to define and modify biologic pathways associated with aging and age-related diseases. Author Stephen B. Kritchevsky, PhD,...
New medications for obesity, such as semaglutide and tirzepatide, are highly effective but can be associated with adverse effects that reduc...
A patent foramen ovale (PFO) is present in approximately 25% of all adults. Author David M. Kent, MD, MS, of Tufts Medical Center and JAMA A...
Approximately 200 000 people are hospitalized for diverticulitis each year in the US, and the incidence of diverticulitis is increasing, par...
A recent Review discusses the epidemiology, risk factors, diagnosis, and treatment of ovarian cancer. William Cliby, MD, and John Weroha, MD...
Early-onset gastrointestinal cancers, typically defined as occurring in patients younger than age 50, are increasing worldwide. A recent JAM...
Approximately 40% of men older than 50 have urinary frequency or urgency that affects their quality of life. Author John T. Wei, MD, MS, of...