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Invest Like the Best with Patrick O'Shaughnessy

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Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boa...

Episodes

20 of 598 episodes

Gabe Stengel - Building Investing Superintelligence - [Invest Like the Best, EP.492]

Gabe Stengel is the co-founder and CEO of Rogo, the AI platform for finance. He believes the best investors will spend the next several year...

64:24Sep 22, 2026

Michael Moritz - Lessons From 40 Years of Investing and Writing - [Invest Like the Best, EP.491]

Michael Moritz led Sequoia Capital for nearly two decades and backed some of the defining companies of the internet era. In his new memoir,...

72:28Sep 16, 2026

Walter Russell Mead - How America Keeps Winning - [Invest Like the Best, EP.490]

My guest today is Walter Russell Mead. Walter is a columnist at the Wall Street Journal and the author of Special Providence and God and Gol...

78:08Sep 8, 2026

Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]

My guest today is Sarah Guo, founder and managing partner of Conviction, the venture firm she built to back AI-native companies from their e...

59:46Sep 1, 2026

Neil Movva - Making AI 10x Cheaper - [Invest Like the Best, EP.488]

My guest today is Neil Movva, founder of Sail. Sail is building what Neil calls a token factory, an inference company designed for a specifi...

78:07Aug 25, 2026

Ben Thompson on Big Tech, China, and the AI Boom Running Out of Money - [Invest Like the Best, EP.487]

My guest today is Ben Thompson, the founder and author of Stratechery. Ben is one of my favorite business thinkers and I love talking to him...

76:16Aug 18, 2026

Eric Vishria - A Decade of Lessons Investing in Software & Hardware - [Invest Like the Best, EP.486]

My guest today is Eric Vishria, a General Partner at Benchmark. Eric has spent his career in software and cloud, and few people know the his...

65:54Aug 11, 2026

Gavin Baker - AI Market Jitters - [Invest Like the Best, EP.485]

My guest today is Gavin Baker, founding partner and CIO of Atreides Management. This is our seventh conversation, and just two months after...

65:04Aug 4, 2026

Sam Altman - How to Make an Abundant Future - [Invest Like the Best, EP.484]

My guest today is Sam Altman, CEO of OpenAI. It's a conversation spanning the history, present, and future of OpenAI, from the origin of Cha...

53:33Jul 28, 2026

Matthew Smith — Natural Gas: The Next Bottleneck - [Invest Like the Best, EP.483]

My guest today is Matthew Smith. Matthew is the founder and CIO of Chronometer Partners, which invests in energy, industrials, materials, po...

56:37Jul 21, 2026

John Kim - How to Raise a Few Billion Dollars - [Invest Like the Best, EP.482]

Today my guest is John Kim. John is one of the world's top and most prolific fundraisers. He was chief client officer at General Catalyst, w...

50:20Jul 14, 2026

Jeremy Giffon - The Billion Dollar PDF - [Invest Like the Best, EP.481]

My guest today is Jeremy Giffon. Jeremy has been on the show before as one of our most popular guests, and this conversation is every bit as...

75:19Jul 7, 2026

Etched - Building AI Hardware to Make Inference Faster and Cheaper - [Invest Like the Best, EP.480]

My guests today are Gavin Uberti and Rob Wachen, the founders of Etched. A few years ago, when they set out to build a better AI chip than t...

87:21Jun 30, 2026

Vlad Barbalat - Investing $120 Billion in Permanent Capital - [Invest Like the Best, EP.479]

My guest today is Vlad Barbalat, the Chief Investment Officer of Liberty Mutual Investments, the $120 billion investment platform that sits...

69:37Jun 23, 2026

Kareem Amin - The Unusual Approach to Company Building - [Invest Like the Best, EP.478]

My guest today is Kareem Amin, co-founder and CEO of Clay. Clay has become one of the fastest-growing software companies of the last few yea...

56:41Jun 16, 2026

Alex Sacerdote - How to Invest Through Technology Cycles - [Invest Like the Best, EP.477]

My guest today is Alex Sacerdote, founder of Whale Rock Capital Management. Whale Rock is a technology focused investment firm that manages...

70:47Jun 9, 2026

Dara Khosrowshahi - Uber's Bet on AVs, AI, and Building a Super-App - [Invest Like the Best, EP.476]

My guest today is Dara Khosrowshahi, the CEO of Uber. Before Uber, Dara ran Expedia for thirteen years. We start with why he took this job i...

67:17Jun 3, 2026

Dan Loeb - Lessons from 30 Years of Investing - [Invest Like the Best, EP.475]

My guest today is Dan Loeb, the founder and CEO of Third Point. Dan started Third Point in 1995 with a few million dollars, and today the fi...

63:03May 28, 2026

Darren Farber on Iran, China, and the Rise of Neoprimes - [Invest Like the Best, EP.474]

My guest today is Darren Farber, and this is his second appearance on the show. Darren is a Managing Partner of Albion River, a defense-focu...

46:19May 26, 2026

Gavin Baker - Watts and Wafers - [Invest Like the Best, EP.473]

My guest today is Gavin Baker, founding partner and CIO of Atreides Management, and this is our sixth conversation. The central theme is wat...

76:51May 20, 2026