Episode 265: ASCO GI Updates: Special Episode

Drs. Shaalan Beg, Shruti Patel, and Emil Lou—the “Only Oncologists in the Building”—offer an in-depth, clinically focused review of the most important research presented at the ASCO GI Annual Meeting. The conversation spans the rising incidence and outcomes of early-onset colorectal cancer, survivorship considerations, and a nuanced discussion of ctDNA in the adjuvant setting for high-risk stage II disease, including whether its role has evolved from purely prognostic to truly predictive. They also critically analyze practice-defining trials such as BREAKWATER in BRAF V600E–mutated metastatic colorectal cancer, COMMIT in dMMR/MSI-H disease, upper GI studies including HORIZON-GEA-01, MATTERHORN, and ILUSTRO, along with meaningful updates in pancreatic and hepatobiliary cancers—ultimately weighing which data should influence clinical practice today versus what remains on the horizon. View content from “The Only Oncologists In the Building.” Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. Watch all Healthcare Unfiltered episodes on YouTube.

You can listen to Episode 265: ASCO GI Updates: Special Episode online on Radio and Podcast. Open the player on this page to stream the available audio.

Episode 265: ASCO GI Updates: Special Episode is an episode from Healthcare Unfiltered by Chadi Nabhan.

This episode is 58:07 long.

This episode was published on Feb 5, 2026.

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