Journal Club #6 POUT and SEMS

Welcome to Episode 6 of our monthly GU Cast Journal Club! Two important papers in upper tract urothelial cancer (the POUT trial of adjuvant chemo post nephro-ureterectomy), and metastatic testicular cancer (the SEMS trial of surgery for early metastatic seminoma). We are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER), along with main GU Cast Hosts, Renu Eapen and Declan Murphy. No prostate cancer today, and go easy on Declan he is struggling with man flu! Links to papers below: 1. Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial Lancet 2020 2. Surgery in Early Metastatic Seminoma: A Phase II Trial of Retroperitoneal Lymph Node Dissection for Testicular Seminoma With Limited Retroperitoneal Lymphadenopathy J Clin Oncol 2023 GU Cast Journal Club is supported by our Partner, MSD, through an unrestricted educational grant. Even better on our YouTube channel About GU Cast Journal Club: Each month, two papers are discussed, each of which are of importance to the GU Oncology community. These may be recent papers, or occasionally we will chose a classic landmark paper in GU Oncology . The objective is to draw attention to important papers in GU Oncology, and critique these in a robust manner . The key target audience is trainees working in Urology, Medical Oncology, Radiation Oncology, Nuclear Medicine, and diagnostic specialties such as Radiology and Pathology. But any of our regular audience are likely to enjoy this Journal Club series.

You can listen to Journal Club #6 POUT and SEMS online on Radio and Podcast. Open the player on this page to stream the available audio.

Journal Club #6 POUT and SEMS is an episode from GU Cast by Professor Declan Murphy & Dr Renu Eapen.

This episode is 26:24 long.

This episode was published on Feb 28, 2026.

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