Journal Club #5 Lamm BCG maintenance and CHAARTED

Happy New Year and welcome to Episode 5 of our monthly GU Cast Journal Club! Today we focus on two classic papers in non-invasive bladder cancer and metastatic prostate cancer. The Lamm RCT of maintenance BCG is a landmark trial for all sorts of reasons, published in J Urol in 2000. And the CHAARTED paper of chemohormonal therapy is the landmark trial of combination therapy in mHSPC, published in NEJM in 2015. We are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER), along with main GU Cast Hosts, Renu Eapen and Declan Murphy. A very lively discussion!! Links to papers below: 1. Maintenance bacillus Calmette-Guerin immunotherapy for recurrent TA, T1 and carcinoma in situ transitional cell carcinoma of the bladder: a randomized Southwest Oncology Group Study J Urol 2000 2. Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer NEJM 2015 GU Cast Journal Club is supported by our Partner, MSD, through an unrestricted educational grant. Even better on our YouTube channel About GU Cast Journal Club: Each month, two papers are discussed, each of which are of importance to the GU Oncology community. These may be recent papers, or occasionally we will chose a classic landmark paper in GU Oncology . The objective is to draw attention to important papers in GU Oncology, and critique these in a robust manner . The key target audience is trainees working in Urology, Medical Oncology, Radiation Oncology, Nuclear Medicine, and diagnostic specialties such as Radiology and Pathology. But any of our regular audience are likely to enjoy this Journal Club series.

You can listen to Journal Club #5 Lamm BCG maintenance and CHAARTED online on Radio and Podcast. Open the player on this page to stream the available audio.

Journal Club #5 Lamm BCG maintenance and CHAARTED is an episode from GU Cast by Professor Declan Murphy & Dr Renu Eapen.

This episode is 30:52 long.

This episode was published on Jan 9, 2026.

Yes. Use the heart button on the episode page to add it to your favorite episodes list.

Yes. This page shows related episodes from GU Cast when more episodes are available from the podcast feed.