Mitochondrial medicine: The biophysics prescription with Lisa Costa-Bir and Dr Christabelle Yeoh

Dr Christabelle Yeoh, integrative medicine physician, joins Lisa Costa-Bir for a deep dive into mitochondria — the organelles influencing nearly every tissue and process in the body. Moving beyond the outdated “powerhouse of the cell” view, Dr Yeoh explains how mitochondria act as processors of energy and evolutionary sentinels of immunity, redox balance, and cellular plasticity. This episode explores how dysfunction manifests clinically — from fatigue and brain fog to autonomic dysregulation, poor vitamin D supplementation uptake, and maternal-line inheritance patterns. Dr Yeoh also shares practical “biophysics prescriptions”: exposure to sunrise and sunset, blocking blue light, eating only in daylight hours, grounding in nature, and regular movement to support mitochondrial quality control. Warm, engaging, and invested in her subject, Dr Yeoh empowers practitioners with insights that place mitochondrial health as the foundation for patient care — and shows why aligning with natural rhythms is essential for resilience and recovery. Covered in this episode: (01:02) Welcome Dr Christabelle Yeoh (03:36) What are the mitochondria? (08:38) ATP and inflammation (12:42) Mitochondria manipulating us? (15:21) Mitohormesis (17:22) Stress (22:46) Mitochondrial dysfunction (28:25) Timeline for mitochondrial change (32:18) Blood testing (36:05) Zeitgebers (41:21) Psychological stress (44:08) Biophysics prescription (48:52) Latest research (50:28) Final remarks Find today's transcript and show notes here: Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: DISCLAIMER: The information provided on fx Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.

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Mitochondrial medicine: The biophysics prescription with Lisa Costa-Bir and Dr Christabelle Yeoh is an episode from FX Medicine Podcast Central by FX Medicine.

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This episode was published on Sep 29, 2025.

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