245. Debunking Sugar Claims: What Dr. Lustig Got Wrong On The Huberman Lab Podcast

This week, Paul talks to Mike Fave, critical care RN, about all things sugar & fructose. They share their thoughts on a recent podcast with Andrew Huberman and Alex Lustig, and why they disagree with certain points made about insulin, fruit juice, and fructose. *Produced by ⁠Mountain Valley Media 00:00:00 Podcast begins 00:04:00 Mike’s background 00:05:15 Diving into fructose 00:13:00 Thoughts on honey and other carb sources 00:27:30 Robert Lustig rebuttal: is fructose addictive? 00:37:40 Fructose & fiber 00:47:00 How fructose affects the mitochondria 00:51:00 Clarifying hyperglycemia vs. a postprandial hyperglycemia 00:56:17 Is insulin the bad guy? 01:12:20 How insulin relates to diabetes, obesity, and insulin resistance 01:23:30 Balancing protein, fat and carbohydrates 01:30:00 Is fructose making us fat? 01:46:00 Final thoughts Connect with Mike: Mikefave.com References: Review article: fructose malabsorption and the bigger picture: A Relationship between Reduced Nucleus Accumbens Shell and Enhanced Lateral Hypothalamic Orexin Neuronal Activation in Long-Term Fructose Bingeing Behavior: A High-Fat Meal, or Intraperitoneal Administration of a Fat Emulsion, Increases Extracellular Dopamine in the Nucleus Accumbens: A Relationship between Reduced Nucleus Accumbens Shell and Enhanced Lateral Hypothalamic Orexin Neuronal Activation in Long-Term Fructose Bingeing Behavior: The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents: Consumption of Raw Orange, 100% Fresh Orange Juice, and Nectar- Sweetened Orange Juice—Effects on Blood Glucose and Insulin Levels on Healthy Subjects: The Effects of Soluble Dietary Fibers on Glycemic Response: An Overview and Futures Perspectives: The Effects of Soluble Dietary Fibers on Glycemic Response: An Overview and Futures Perspectives: Formation of Fructose-Mediated Advanced Glycation End Products and Their Roles in Metabolic and Inflammatory Diseases: Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM: Glucagon and type 2 diabetes: the return of the alpha cell: Insulin, growth hormone and sport: Effect of Mild Physiologic Hyperglycemia on Insulin Secretion, Insulin Clearance, and Insulin Sensitivity in Healthy Glucose-Tolerant Subjects: Fructose metabolism in humans – what isotopic tracer studies tell us: Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides: Review article: fructose malabsorption and the bigger picture: Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice: Fructose Promotes Leaky Gut, Endotoxemia and Liver Fibrosis through CYP2E1-Mediated Oxidative and Nitrative Stress:

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245. Debunking Sugar Claims: What Dr. Lustig Got Wrong On The Huberman Lab Podcast is an episode from Fundamental Health with Paul Saladino, MD by Paul Saladino, MD.

This episode is 01:54:45 long.

This episode was published on Jan 25, 2024.

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