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Structural characterisation of transcription and replication through cisplatin lesioned DNA artwork
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Structural characterisation of transcription and replication through cisplatin lesioned DNA

Fakultät für Chemie und Pharmazie - Digitale Hochschulschriften der LMU - Teil 02/06 by Ludwig-Maximilians-Universität München

Feb 7, 20080Education

Replication of the genome is strongly inhibited when high fidelity DNA polymerases encounter unrepaired DNA lesions, which can not be processed. The highly stringent active sites of these polymerases are unable to accomm...