EFR 928: How to Prevent Alzheimer's and Protect Your Brain and How to Get Smarter at Any Age with Dr. Majid Fotuhi

This episode is brought to you by AX3 Life , Strong Coffee Company and WHOOP. Today we sit down with neurologist and brain health expert Majid Fotuhi , MD, PhD, author of The Invincible Brain , to challenge conventional thinking about Alzheimer's disease and cognitive decline. Dr. Fotuhi explains why Alzheimer's may not be a single disease but rather the result of multiple processes—including inflammation, poor sleep, metabolic dysfunction, and lifestyle factors—that accumulate over time. The conversation explores the science behind brain shrinkage, the role of sleep in clearing toxins from the brain, why exercise may be one of the most powerful tools for cognitive health, and the five pillars of brain fitness: exercise, sleep, nutrition, stress reduction, and brain training. He also shares clinical research showing that targeted lifestyle changes can significantly improve cognitive performance and even increase hippocampal volume in patients with mild cognitive impairment, offering a hopeful perspective on protecting and strengthening the brain as we age. ----- 00:00 – Why Alzheimer's may not be a single disease 02:34 – The "soup of problems" explanation for Alzheimer's 03:21 – Why many dementia diagnoses miss treatable causes 04:01 – Treating lifestyle factors that affect brain health 06:30 – Understanding mild cognitive impairment (MCI) 10:15 – Brain shrinkage and inflammation explained 15:12 – Why lifestyle affects brain aging 20:40 – The role of exercise in brain health 28:22 – How exercise helps grow new neurons 29:11 – Exercise and the brain's waste-clearing system 30:03 – Why sleep is critical for brain detox 31:20 – The five pillars of brain health 33:45 – Why there is no "miracle cure" for brain health 38:10 – How small daily habits compound over time 45:44 – Research showing the brain can grow again 48:11 – MCI vs Alzheimer's diagnosis explained 49:28 – Risk factors that can accelerate dementia 50:13 – Clinical results improving cognitive performance 52:00 – Ever Forward ----- Episode resources: Save 20% on the super-antioxidant astaxanthin from AX3 Life with code EVERFORWARD Save 15% on organic coffee and lattes from Strong Coffee Company with code CHASE Get a FREE WHOOP 5.0 sleep and activity tracker Watch and

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EFR 928: How to Prevent Alzheimer's and Protect Your Brain and How to Get Smarter at Any Age with Dr. Majid Fotuhi is an episode from Ever Forward Radio | Fitness, Nutrition, Mindset, Entrepreneurship & Self-Help by Chase Chewning.

This episode is 01:21:23 long.

This episode was published on Mar 16, 2026.

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