“No casual experiments”: Inside a legendary psychedelics lab

In a small, bunker-like laboratory in the East Bay hills, Alexander “Sasha” Shulgin created some of the world’s most powerful psychedelic drugs. Astonishingly, he didn’t try to hide his activities. On the contrary, Sasha published instruction manuals on how to make his mind-expanding compounds, and his farm in Lafayette became a mecca for scientists, therapists, artists, and others who were drawn into his world of pharmacological experimentation. Along with his wife, Ann, Sasha was a pioneer who helped lay the groundwork for the therapeutic use and decriminalization of psychoactive drugs that is unfolding today. Although Sasha and Ann both passed away, their legacy is being carried on at the Shulgin Farm, which continues to be a space for psychedelic research, educational gatherings, and other activities. On May 2, the Shulgin Foundation will be launching “MDMA: From Molecule to Movement” at the Berkeley Alembic, an exhibit tracing the history of Shulgin’s influence in synthesizing and spreading the drug now known widely as “molly.” This episode features interviews with Wendy Tucker, chair of the Shulgin Foundation, Paul Daley, co-founder of the Alexander Shulgin Research Institute, and Shulgin Foundation director Megan Bowers. Get comfortable, because we’re going deep with this one! To see photos and links related to this episode, visit: Don’t forget to follow the East Bay Yesterday Substack for updates on events, boat tours, exhibits, and other local history news: Donate to keep this show alive:

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“No casual experiments”: Inside a legendary psychedelics lab is an episode from East Bay Yesterday by East Bay Yesterday.

This episode is 01:15:25 long.

This episode was published on Apr 29, 2026.

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