Open Notebook Science - Falcipain-2 Preliminary Results

This talk was presented by Jean-Claude Bradley at the American Chemical Society meeting in Philadelphia on August 20, 2008. An introduction to Open Notebook Science is presented followed by an illustration of how ONS can be used in drug discovery. New data relating to the anti-malarial activity of Ugi products on 2 falcipain-2 docking sites is detailed. The docking calculations were provided by Rajarshi Guha and the enzyme and in vitro assays on Plasmodium falciparum were provided by Phil Rosenthal and Jiri Gut. Most of the syntheses were carried out by Khalid Mirza in the Bradley group. audio (mp3) Google Video screencast Open Notebook Science and Preliminary Falcipain-2 Results View SlideShare presentation or Upload your own. (tags: reaction ugi )

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Open Notebook Science - Falcipain-2 Preliminary Results is an episode from Drexel CoAS talks mp3 podcast by Jean-Claude Bradley.

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This episode was published on Aug 22, 2008.

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