
One Molecule, Two Opioid Receptors - Joseph Kim
Dr. Joseph Kim solved cryo-EM structures of mu and kappa opioid receptors bound to the same small molecule — and found it does something dif...
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We bring you closer to dedicated scientists who work tirelessly to help understand GPCR pathophysiology.

Dr. Joseph Kim solved cryo-EM structures of mu and kappa opioid receptors bound to the same small molecule — and found it does something dif...

How does ligand binding at the extracellular pocket of a GPCR reshape signaling on the intracellular side? Biased agonism is often measured...

Conserved neuropeptide Y GPCRs orchestrate both feeding and mating behaviors in mosquitoes, with direct translational parallels to human gut...

Key Takeaways How does the precise localization of GPCRs in lipid rafts reshape drug discovery strategy? Examine implications for functional...

Episode Summary Potent in vitro hits often fail in vivo—Martin Marro details how robust assay choice and pathway deconvolution can revive GP...

GPCR tools don’t move the field forward unless researchers can actually use them. This episode breaks down how collaboration turns probes in...

Chemical probes are reshaping how we map GLP-1R in real time — revealing receptor pools antibodies can’t reliably capture. This is Episode 2...

Precise receptor mapping is reshaping how we understand incretin biology. David Hodson explains how GPCR-targeted chemical probes reveal whe...

What makes Monash a model for modern pharmacology? Dr. Michelle Halls reveals how collaboration, mentorship, and receptor organization shape...

Predicting, not just explaining, can change how we design GPCR-targeted drugs. Jens Carlsson reveals how modeling bridges structure, functio...

🔬 What if you could track GPCR internalization—no wash, high-throughput, and in endogenous systems? Discover how Dr. Eric Trinquet and Revv...

What if a failed med school plan led to a biotech breakthrough? Ajay Yekkirala shares how GPCRs, AI, and scientific curiosity are reshaping...

When fentanyl slows your breath and xylazine traps it, the clock starts ticking. PhD candidate Catherine Demery takes us inside her fight to...

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Episode 166 of the Dr. GPCR Podcast features Benjamin Clements, a postdoctoral fellow at the University of Michigan, who brings fresh insigh...

In this episode of the Dr. GPCR Podcast, we step outside the lab to talk about what keeps research-driven organizations running behind the s...

In this science-focused episode of the Dr. GPCR podcast, we meet Dr. Ian Chronis, a freshly minted PhD from the University of Michigan. Whil...

Ask the Right GPCR Question: A Conversation with Prof. Dmitry VeprintsevIn this episode, Yamina sits down with Prof. Dmitry Veprintsev, a mo...

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