#202 Dementia Part 2: Gray Matters Segment

Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help . In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them. • Do cholinesterase inhibitors really work? • What should clinicians know about lecanemab and donanemab before referring patients? • How much benefit should we expect and for how long? • When should you deprescribe dementia medications ? 🔹 Sponsor: Caraway’s cookware set is a favorite for a reason. For 10% off, go to Carawayhome.com/ CoreIM or use code CoreIM at checkout. 🔹 Transcript and Shownotes 02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia? 09:41 | Deep Dive 2: Prescribing medications for cognitive decline 29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline 35:46 | Deep Dive 4: Planning for an uncertain future Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant Find the best disability insurance for you: Our Sponsors: * Check out FIGS: * Click for 15% off Premium Starter Kit at Branch Basics: Advertising Inquiries: Privacy & Opt-Out:

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#202 Dementia Part 2: Gray Matters Segment is an episode from Core IM | Internal Medicine | Medical Education | FOAMed | Family Medicine | Physician Assistant | R by Core IM Team.

This episode is 47:16 long.

This episode was published on Mar 12, 2026.

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