Molecular modelling, 2012, Lecture 7
Two case studies involving the principles of stereochemical design
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Audio and video podcasts from undergraduate lecture courses given in the Chemistry Department. The audio materials are annotated as "enhanced" Podcasts with full lecture notes, handouts, and...
Episodes
20 of 112 episodesConformational analysis, 2012, Lecture 5
Cyclo-octane, trans-cyclo-octene, and atripisomerism. Caroyophyllene and biphenyls.
Molecular modelling, 2012, Lecture 6
Transition state modelling; reaction coordinates and aromatic electrophilic substitution. Pyridine, concerted vs Wheland intermediates. The...
Molecular modelling, 2012, Lecture 5
The analysis of wave functions, including molecular orbitals, electrostatic potentials, QTAIM critical points, and the NCI method.
Molecular modelling, 2012, Lecture 4
Overview of quantum mechanical methods, the Hamiltonian, the best set and extrapolative methods.
Molecular modelling, 2012, Lecture 3
The mechanics force field, how it is used to optimize molecular geometries, and a case study.
Molecular modelling, 2012, Lecture2
The techniques of molecular visualisation, and the sources of coordinates.
Conformational analysis, 2012, Lecture 4.
Conformational analysis of 3,4,5 and 6-membered rings.
Molecular modelling, 2012, lecture 1
General aspects of molecular modelling, including scales, coordinates, properties and reactivity.
Conformational analysis, 2012, Lecture 3.
The conformational preferences of alikeness, aldehydes, ketones, esters and amides.
Conformational analysis, 2012. Lecture 2.
The factors responsible for the conformation of alkanes and heterosubstituted alkanes.
Conformational analysis, 2012. Lecture 1.
Historical background to conformational analysis, and Barton's contributions. The stereo electronic theory of conformational analysis.
Pericyclic reactions, 2012, lecture 1
Hiostorical preamble, characteristic properties and examples of the major types of pericyclic reactions
Pericyclic reactions, 2012, lecture 5
Examples of sigma tropic reactions, illustrating the equivalence between inversion and antarafacial modes.
Pericyclic reactions, 2012, lecture 4
Examples of pericyclic additions and eliminations, with two joined up case studies.
Pericyclic reactions, 2012, lecture 3
A number of examples of electrocyclic pericyclic reactions.
Pericyclic reactions, 2012, lecture 2
The theory of orbital symmetry, with selection rules derived from transition state aromaticity
Conformational analysis, 2011, lecture 6
Cyclo-octane, trans cyclo-octene, how to resolve it into configurational isomers, and atropisomerism in caryophyllene. Restricted rotation i...
Conformational analysis, 2011: lecture 5
Conformational analysis of rings, and sugars.
Conformational analysis, 2011: lecture 4
Analysis of cyclopropane, cyclobutane, cyclopentane and cyclohexane, including ring-locking with large groups and anti-periplanar relationsh...