Monthly Therapy for Hypertension: Insights From the Phase II KARDINAL Trial

Steven Nissen, MD, and Luke Laffin, MD, discuss late-breaking data from the Phase II KARDINAL Trial evaluating Tonlamarsen, a once-monthly therapeutic for uncontrolled multidrug therapy. They review study design, blood pressure outcomes and the potential clinical role of long-acting injectable therapies to address adherence gaps in real-world hypertension management. View current clinical trials. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

You can listen to Monthly Therapy for Hypertension: Insights From the Phase II KARDINAL Trial online on Radio and Podcast. Open the player on this page to stream the available audio.

Monthly Therapy for Hypertension: Insights From the Phase II KARDINAL Trial is an episode from Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals by Cleveland Clinic Heart & Vascular Institute.

This episode is 10:34 long.

This episode was published on Apr 2, 2026.

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