BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas

Support the show to get full episodes, full archive, and join the Discord community . The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership . Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org . Nikolay Kukushkin is an associate professor at New York University, and a senior scientist at Thomas Carew’s laboratory at the Center for Neural Science. He describes himself as a "molecular philosopher", owing to his day job as a molecular biologist and his broad perspective on how it "hangs together", in the words of Wilfrid Sellers, who in 1962 wrote, “The aim of philosophy, abstractly formulated, is to understand how things in the broadest possible sense of the term hang together in the broadest possible sense of the term”. That is what Niko does in his book One Hand Clapping: Unraveling the Mystery of the Human Mind . This book is about essences across spatial scales in nature. More precisely, it's about giving names to what is fundamental, or essential, to how things and processes function in nature. Niko argues those essences are where meaning resides. That's very abstract, and we'll spell it out more during the discussion. But as an example at the small scale, the essences of carbon and oxygen, respectively, are creation and destruction, which allows metabolism to occur in biological organisms. Moving way up the scale, following this essence perspective leads Niko to the conclusion that there is no separation between our minds and the world, and that instead we should embrace the relational aspect of mind and world as a unifying principle. On the way, via evolution, we discuss many more examples, plus some of his own work studying how memory works in individual cells, not just neurons or populations of neurons in brains. Niko's website . Twitter: @niko_kukushkin . Book: One Hand Clapping: Unraveling the Mystery of the Human Mind Read the transcript . 0:00 - Intro 9:28 - Studying memory in cells 10:14 - Who the book is for 17:57 - Studying memory in cells 21:53 - What is memory? 29:49 - Book 29:52 - How the book came about 37:56 - Central message of the book 44:07 - Meaning in nature 49:09 - Meaning and essence 51:55 - Multicellularity and ant colonies 57:43 - Eukaryotes and complexification 1:03:38 - Why do we have brains? 1:06:17 - Emergence 1:10:58 - Language 1:12:41 - Human evolution 1:14:41 - Artificial intelligence, meaning and essences 1:25:49 - Consciousness

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BI 222 Nikolay Kukushkin: Minds and Meaning from Nature’s Ideas is an episode from Brain Inspired by Paul Middlebrooks.

This episode is 01:28:26 long.

This episode was published on Oct 8, 2025.

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