405: 405 Winchester-Roosevelt's Medicine Gun For Lions

We're talking about the 405 Winchester today, which is President Theodore Roosevelt's legendary medicine gun for lions. To this day, that statement remains one of the most effective presidential endorsements of any product ever. We will discuss more details of how that cartridge performed for Theodore Roosevelt in Africa, plus I'll also cover the history and performance specs of the cartridge, it's strengths and limitations, some other hunting stories involving it, and some recommendations on the best use cases for the round. Sponsor: Get in touch with me to make your Africa hunting dreams come true on a hunt in South Africa. We offer outstanding hunting safaris, simplified hunt logistics, assistance with many of the pain points associated with a hunt, and up front pricing with no extra fees. We just opened bookings for 2027 and still have a few spots remaining for May, October, and November 2026. Visit bestsafarihunt.com or email me at john@thebiggamehuntingblog.com to learn more. Make sure to state that you're a podcast listener and I'll give you a special bonus! North Fork produces several projectiles that are outstanding choices for the 405 Winchester that take the performance of the cartridge to the next level. You can purchase North Fork bullets in the .411 and .413 bore diameters (as well as many others: .308, .338, .375 caliber, etc.) directly from the North Fork web site , from MidwayUSA , or from our network of other distributors all over the world. Please hit that "

You can listen to 405: 405 Winchester-Roosevelt's Medicine Gun For Lions online on Radio and Podcast. Open the player on this page to stream the available audio.

405: 405 Winchester-Roosevelt's Medicine Gun For Lions is an episode from Big Game Hunting Podcast: Rifles, Calibers & Muzzleloaders For Deer, Elk & African Game by John McAdams.

This episode is 47:13 long.

This episode was published on Jan 8, 2026.

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