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Big Fat Negative: TTC, fertility, infertility and IVF

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Big Fat Negative is the podcast about IVF, infertility and the trials of TTC - aka trying for a baby. Co-hosted by journalists and friends Emma Forsyth Haslett and Gabriella Griffith, the sh...

Episodes

20 of 150 episodes

Genevieve Thurley: 'I was not going to celebrate until the baby was in my arms'

Genevieve Thurley is a busy woman, what with her 1 million followers and career as a makeup artist and content creator. But today, she's mak...

1:11:34Jun 22, 2026

Cathy Adams: Deciding when enough is enough

Cathy Adams is the travel news features editor for The Times and Sunday Times -- and also a person who has spent years trying to conceive he...

1:06:33Jun 15, 2026

What sperm can tell you about your partner's health

This week we're joined by Tristan Taylor, the founder of Mandrology, who is biohacking his way to sperm health. He explains why sperm qualit...

55:03Jun 9, 2026

How to prevent 10,000 miscarriages a year

Oonagh Pickering is one of the research nurses at Tommy's whose study on graduated miscarriage care has already changed how the Scottish NHS...

53:14Jun 2, 2026

Martha de Lacey: 'You give yourself this story of why things happened'

The sourdough baker Martha de Lacey joins us this week: she has run the full gamut of infertility experiences, from going solo to recurrent...

49:18May 19, 2026

Sheyi Martins-Allen on the pain of secondary infertility

She's a performer, musician and wickedly funny creator: Sheyi Martins-Allen joins us to talk about her experience of secondary infertility,...

54:46May 12, 2026

The Fertility Disconnect: A Wild Nutrition special

SPECIAL EPISODE SPONSORED BY WILD NUTRITION. Gabby and Emma swanned off to London last week to attend the launch of a new report by Wild Nut...

53:34May 11, 2026

Dr Helen O'Neill: The woman who is changing what we know about hormones

Dr Helen O'Neill is many things: a mirror twin, an associate professor in reproductive and molecular genetics at UCL, and also the co-founde...

45:08May 6, 2026

Kate-Lois Elliott: TTC, but still laughing

The comedian Kate-Lois Elliott joins us today to talk about how she's balancing the demands of a comedy career with TTC and infertility - an...

1:00:15Apr 28, 2026

Improving male fertility: 'I even went commando'

Jacky Maughan had been an international DJ before he and his wife, Eleanor, started trying for a baby. "His lifestyle was party, party, drin...

56:59Apr 21, 2026

Solo, queer and trying for a baby

The actor and writer Natalie Walmsley tells us their story of IUI, ectopics and queer conception - and how they are turning their story into...

58:45Apr 14, 2026

Dr Shanna Swan from The Plastic Detox

We're back! (Sort of). Today we're interviewing Dr. Shanna Swan, the presenter of The Plastic Detox, a new Netflix documentary examining the...

47:34Mar 16, 2026

Bonus: Dr. Jessica Zucker on miscarriage

You might know Dr Jessica Zucker better as @IHadAMiscarriage, the campaigner who helped thousands of women to tell their stories of loss. Sh...

45:17May 2, 2025

BONUS: Emily Oster

We're back for one night only and we're joined by economist, author, data scientist and all-round HERO Emily Oster, who tells us what the da...

42:47Jan 31, 2025

Merry Christmas!

Well, that's a wrap for series 7. To celebrate, Gabby and Emma are raising a festive glass and answering questions from listeners. They're a...

50:57Dec 17, 2024

Amber Izzo and Katie Rollings on ending the IVF postcode lottery

We've heard some heart-breaking stories about the IVF postcode lottery - people who've aged out of their ICB's limit as they tried to lose w...

45:42Dec 10, 2024

It's Louise Brown!!!!

This week we are lucky enough to be joined by THE Louise Joy Brown, the first IVF baby. She talks about how her mum felt about going through...

37:56Dec 3, 2024

Aisha Balesaria on childlessness not by choice

This week we're talking to Aisha Balesaria, aka Mind Body Revival Coach, about childlessness not by choice. She discusses her chronic endome...

48:04Nov 26, 2024

'Joy' creators Rachel Mason and Jack Thorne

Surprise! We're here on a Friday to give you a little something extra: an interview with the screenwriters of the new Netflix movie Joy , wh...

34:58Nov 22, 2024

Jessica Hepburn returns

Last time we spoke to the author, adventurer and arts producer Jessica Hepburn was way back in 2019, when we talked about how she swam the E...

53:40Nov 19, 2024