The Man Who Couldn’t Stop Gaining Weight | A Medical Mystery
A previously healthy 21-year-old shows up with seven months of headaches and 30-plus pounds of weight gain he can’t explain. He’s eating the...
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A previously healthy 21-year-old shows up with seven months of headaches and 30-plus pounds of weight gain he can’t explain. He’s eating the...
Every couple of years a new headline warns that the protein you eat is quietly hurting you. This year the target is your kidneys. Before tha...
Is weight loss really just Calories in, Calories out? The equation is true, but "just count your Calories" is bad advice for most people, an...
Obesity roughly tripled in about 60 years, and the genes didn't change in that time. So if body weight isn't a willpower problem, what is it...

Once a month we answer Barbell Medicine Plus subscribers’ questions on the Direct Line. This is a free look at June’s episode. We start with...
Is there really a “menopause-specific” way to train, eat, and supplement — or is most of it marketing? In the finale of our 4-part menopause...
Most women in 2026 are told menopause affects everything, the weight, the belly fat, the bones, the heart, the brain, and that the fix is ho...
The story goes that hard exercise is risky for women, and that the idea is ancient. Both halves fall apart on contact. In this solo episode,...
In 1889 a French physiologist injected himself with guinea pig and dog testicle extract and published a claim of self-rejuvenation in The La...
This is the free preview of the May 2026 Direct Line, our monthly AMA for Barbell Medicine Plus subscribers. Three reader questions answered...
Most cases of low testosterone in modern men are not a problem with the testes. The number is downstream of body composition, sleep, and ene...
Three weeks of stalled squats. The conventional answer is to switch programs because you've crossed into intermediate territory. The data sa...
Out of 32 symptoms commonly attributed to low testosterone, only 3 actually correlate with it. All three are sexual. The other 29 — fatigue,...

Stop a GLP-1 and about two thirds of the weight loss comes back within a year. Three randomized withdrawal trials (SURMOUNT-4, STEP 1 extens...
Every week there's a new headline saying men are losing testosterone. A quarter of men now start testosterone replacement therapy without ev...
A 43-year-old man starts exercising and ends up in the ER with a CK over 100x the upper limit of normal. His doctor says it’s from training....
In 2022, researchers conducted the most rigorous systematic review ever performed on overtraining syndrome — looking specifically for contro...
In this free preview of the March 2026 Direct Line AMA. Drs. Feigenbaum and Baraki cover: VO2 max versus cardiorespiratory fitness for longe...
You can have a completely normal BMI and be on your way to cardiovascular disease, type 2 diabetes, and metabolic syndrome without triggerin...
A fit, healthy 39-year-old was nearly sent for a liver biopsy. The cause? Was it that he went to the gym before every blood draw or because...